Department of Oral Diagnosis, Piracicaba Dental School, State University of Campinas, Av. Limeira, 901 - Areião, Piracicaba, SP, 13414-903, Brazil.
MackGraphe - Graphene and Nanomaterials Research Center, Mackenzie Presbyterian University, São Paulo, SP, Brazil.
Clin Oral Investig. 2020 May;24(5):1695-1700. doi: 10.1007/s00784-019-03027-3. Epub 2019 Jul 23.
To evaluate the artifact expression of a new material-polylactic acid (PLA)/hydroxyapatite (HA)/graphene oxide (GO) nanocomposite-and compare it with that of commonly used dental materials, using cone-beam computed tomography.
Cylinders of amalgam alloy, metal alloy, titanium, gutta-percha, and PLA/HA/GO were individually placed in the center of an acrylic phantom. Three images of each phantom + cylinder set were acquired using a Picasso Trio unit (Vatech, Hwaseong, South Korea) set at 90 kVp, 3.7 mA, 0.2 mm voxel size, and 12 × 8.5 cm FOV. Three images of a control group (sound phantom) were also obtained. Eight ROIs were established in each image to evaluate the standard deviation (S.D.) of gray values in the ImageJ Software. The Kruskal-Wallis test with the Student-Newman-Keuls post hoc was employed, considering a significance level of 5%.
There were no significant differences in S.D. between the control and PLA/HA/GO images (p = 0.712). Both control and PLA/HA/GO showed fewer image artifacts than the other materials (p < 0.05). The images of the amalgam alloy did not differ from the metal alloy images (p = 0.691), showing more artifacts than the gutta-percha (p = 0.028) and titanium (p = 0.051).
The PLA/HA/GO produced fewer artifacts and a better-quality image than the other tested materials.
The PLA/HA/GO has physical and biological properties similar to those of dental materials. Since it has produced fewer image artifacts, this new nanocomposite may be employed in the near future, enhancing the diagnosis in CBCT.
使用锥形束计算机断层扫描（CBCT）评估新型材料-聚乳酸（PLA）/羟基磷灰石（HA）/氧化石墨烯（GO）纳米复合材料的伪影表达，并将其与常用牙科材料进行比较。
将汞合金合金、金属合金、钛、牙胶和 PLA/HA/GO 圆柱体分别放置在丙烯酸体模的中心。使用 Picasso Trio 设备（韩国华城的 Vatech）在 90 kVp、3.7 mA、0.2 mm 体素大小和 12×8.5 cm FOV 下，分别对每个体模+圆柱体组的三个图像进行采集。还获得了一个对照组（正常体模）的三个图像。在每个图像中建立了 8 个 ROI，以在 ImageJ 软件中评估灰度值的标准偏差（S.D.）。采用 Kruskal-Wallis 检验和 Student-Newman-Keuls 事后检验，显著性水平为 5%。
在 S.D.方面，对照组和 PLA/HA/GO 图像之间没有差异（p=0.712）。对照组和 PLA/HA/GO 均比其他材料显示出更少的图像伪影（p<0.05）。汞合金合金的图像与金属合金的图像没有差异（p=0.691），显示出比牙胶（p=0.028）和钛（p=0.051）更多的伪影。
与其他测试材料相比，PLA/HA/GO 产生的伪影更少，图像质量更好。
PLA/HA/GO 的物理和生物学特性与牙科材料相似。由于它产生的图像伪影较少，这种新型纳米复合材料可能在不久的将来得到应用，从而增强 CBCT 的诊断。
