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直肠手术后骶前脓肿应用海绵内治疗的效果。

Effectiveness of endosponge therapy for the management of presacral abscesses following rectal surgery.

机构信息

Department of Gastroenterology and Hepatology, Isala, Zwolle, The Netherlands.

Department of Surgery, Isala, Zwolle, The Netherlands.

出版信息

Tech Coloproctol. 2019 Jun;23(6):551-557. doi: 10.1007/s10151-019-02007-9. Epub 2019 Jul 23.

Abstract

BACKGROUND

Anastomotic leak after rectal surgery is reported in 9% (range 3-28%) of patients. The aim of our study was to evaluate the effectiveness of endosponge therapy for anastomotic. Endpoints were the rate of restored continuity and the functional bowel outcome after anastomotic leakage.

METHODS

This was a multicenter retrospective observational cohort study. All patients with symptomatic anastomotic leakage after rectal surgery who had endosponge therapy between January 2012 and August 2017 were included. Functional bowel outcome was measured using the low anterior resection syndrome (LARS) score system.

RESULTS

Twenty patients were included. Eighteen patients had low anterior resection (90%) for rectal cancer. A diverting ileostomy was performed at primary surgical intervention in 14 patients (70%). Fourteen patients (70%) were treated with neoadjuvant (chemo-)radiotherapy. The median time between primary surgical intervention and first endosponge placement was 21 (5-537) days. The median number of endosponge changes was 9 (2-28). The success rate of the endosponge treatment was 88% and the restored gastrointestinal continuity rate was 73%. A chronic sinus occurred in three patients (15%). All patients developed LARS, of which 77% reported major LARS.

CONCLUSIONS

Endosponge therapy is an effective treatment for the closure of presacral cavities with high success rate and leading to restored gastrointestinal continuity in 73%. However, despite endosponge therapy many patients develop major LARS.

摘要

背景

直肠手术后吻合口漏的发生率为 9%(范围 3-28%)。我们的研究目的是评估内海绵治疗吻合口的有效性。终点是吻合口漏后连续性恢复的比率和功能性肠结果。

方法

这是一项多中心回顾性观察队列研究。纳入 2012 年 1 月至 2017 年 8 月期间接受内海绵治疗的直肠手术后有症状吻合口漏的所有患者。采用低位前切除术综合征(LARS)评分系统测量功能性肠结果。

结果

共纳入 20 例患者。18 例(90%)因直肠癌行低位前切除术。14 例(70%)患者在初次手术干预时行预防性回肠造口术。14 例(70%)患者接受新辅助(放)化疗。初次手术干预和首次放置内海绵之间的中位时间为 21 天(5-537 天)。内海绵更换的中位数为 9 次(2-28 次)。内海绵治疗的成功率为 88%,胃肠连续性恢复率为 73%。3 例(15%)患者出现慢性窦道。所有患者均发生 LARS,其中 77%报告有主要 LARS。

结论

内海绵治疗是一种有效的治疗方法,可有效闭合骶前间隙,成功率高,可恢复 73%的胃肠连续性。然而,尽管采用内海绵治疗,许多患者仍会发生主要的 LARS。

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