Radiation Dose for Multiregion CT Protocols: Challenges and Limitations.

The purpose of this study was to devise a method for classification of individual chest and abdomen-pelvis CT doses for multiregion CT. A retrospective analysis of volume CT dose index (CTDI) and dose-length product (DLP) associated with chest (150 adult patients), abdomen-pelvis (150 patients), and multiregion combined chest-abdomen-pelvis CT (210 patients; 60 single-run chest-abdomen-pelvis CT; 150 split-run with separate chest and abdomen-pelvis CT). All 510 CT examinations were performed with one of four MDCT scanners (64-, 64-, 128-, 256-MDCT). CTDI, DLP, and scan length were recorded. Scan lengths were obtained for these 510 CT examinations and for an additional 7745 examinations of patients at another institution. Data were analyzed by ANOVA and ROC analysis. The respective DLPs (chest, 258-381 mGy · cm; abdomen-pelvis, 360-433 mGy · cm; single-run chest-abdomen-pelvis, 595-636 mGy · cm) and scan lengths (chest, 31-33 cm; abdomen-pelvis, 45-46 cm; single-run chest-abdomen-pelvis, 63-65 cm) for chest, abdomen-pelvis, and multiregion combined chest-abdomen-pelvis CT were significantly different ( < 0.0001). For split-run, chest-abdomen-pelvis CT, scan lengths and dose indexes for individual body regions were not different from those of single-body-region CT ( > 0.05). ROC analysis of chest and abdomen examinations showed an ideal scan length threshold of 38 cm to differentiate abdomen-pelvis CT from chest CT with accuracy of 97.39% and an AUC of 0.9764. Despite interscanner variabilities in CT radiation doses, shorter scan length for chest than for abdomen-pelvis CT enables accurate binning of radiation doses for split-run combined chest-abdomen-pelvis CT.