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[通过SEGA工具评估的衰弱对患有急性冠状动脉综合征的八旬老人一年预后的价值:PROSECO研究]

[Prognostic value at one year of frailty as evaluated by the SEGA instrument for octogenarians presenting an acute coronary syndrome: PROSECO study].

作者信息

Faroux Laurent, Nazeyrollas Pierre, Acsente Camelia, Novella Jean-Luc, Jolly Damien, Metz Damien, Drame Moustapha

机构信息

Service de cardiologie, Hôpital Robert Debré, CHU Reims, Reims, France, EA3797 Vieillissement, Fragilité (VieFra), Hôpital Robert Debré, CHU Reims, Reims, France.

EA3797 Vieillissement, Fragilité (VieFra), Hôpital Robert Debré, CHU Reims, Reims, France, Service de gériatrie, Hôpital Maison Blanche, CHU Reims, Reims, France.

出版信息

Geriatr Psychol Neuropsychiatr Vieil. 2019 Sep 1;17(3):271-278. doi: 10.1684/pnv.2019.0810.

DOI:10.1684/pnv.2019.0810
PMID:31339491
Abstract

The SEGA instrument has demonstrated good performance in screening for frailty. However, its predictive ability in elderly patients presenting with acute coronary syndrome have never been evaluated. We aimed to study the prognostic value at one year of the frailty level assessed by the SEGA instrument, in a population of patients aged 80 years old or more hospitalised for acute coronary syndrome. All consecutive patients aged 80 years or older hospitalised for myocardial infarction type 1 between November 2016 and October 2017 were included. All underwent standardised geriatric assessment including estimation of frailty by the SEGA instrument. The primary outcome was the time to death from any cause. In all 64 patients were included for a mean age of 85.3±4 years. Using the SEGA instrument, 24% patients were classified "frail" and 44% "very frail"; 18 (28%) deaths were observed during follow-up. When adjusted for patient age, body mass index and arterial hypertension, survival status was not significantly related with frailty status (HR=1.1, 95% CI=0.4-3.1, p=0.8).

摘要

世嘉仪器在筛查衰弱方面已显示出良好的性能。然而,其对急性冠状动脉综合征老年患者的预测能力从未得到评估。我们旨在研究世嘉仪器评估的衰弱水平在80岁及以上因急性冠状动脉综合征住院的患者群体中一年的预后价值。纳入了2016年11月至2017年10月期间所有因1型心肌梗死住院的80岁及以上连续患者。所有患者均接受了标准化的老年评估,包括使用世嘉仪器评估衰弱情况。主要结局是任何原因导致的死亡时间。共纳入64例患者,平均年龄为85.3±4岁。使用世嘉仪器,24%的患者被分类为“衰弱”,44%为“非常衰弱”;随访期间观察到18例(28%)死亡。在对患者年龄、体重指数和动脉高血压进行调整后,生存状况与衰弱状况无显著相关性(风险比=1.1,95%置信区间=0.4-3.1,p=0.8)。

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