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[恶性周围神经鞘膜瘤的治疗:病例报告及文献综述]

[Treatment of malignant peripheral nerve sheath tumors: case reports and a literature review].

作者信息

Konovalov N A, Korolishin V A, Asyutin D S, Timonin S Yu, Shults M A, Solenkova A V, Zakirov B A, Batyrov A A

机构信息

Burdenko Neurosurgical Center, Moscow, Russia.

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 2019;83(3):64-72. doi: 10.17116/neiro20198303164.

Abstract

Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that develop from peripheral nerve sheath cells (T. Hirose, B.W. Scheithauer). These tumors are characterized by aggressive growth with an unfavorable outcome and may develop de novo or through malignant transformation of schwannomas, neurofibromas, or ganglioneuromas. MPNSTs are characterized by a rapid course and a poor prognosis. In this article, we reported cases of patients with malignant peripheral nerve tumors of the brachial plexus trunks and spinal localization.

摘要

恶性外周神经鞘瘤(MPNSTs)是起源于外周神经鞘细胞的软组织肉瘤(T. Hirose,B.W. Scheithauer)。这些肿瘤的特点是生长迅速且预后不良,可原发发生,也可由神经鞘瘤、神经纤维瘤或神经节神经瘤恶变而来。MPNSTs病程进展迅速,预后较差。在本文中,我们报告了臂丛神经干和脊柱部位恶性外周神经肿瘤患者的病例。

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