Konovalov N A, Korolishin V A, Asyutin D S, Timonin S Yu, Shults M A, Solenkova A V, Zakirov B A, Batyrov A A
Burdenko Neurosurgical Center, Moscow, Russia.
Zh Vopr Neirokhir Im N N Burdenko. 2019;83(3):64-72. doi: 10.17116/neiro20198303164.
Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that develop from peripheral nerve sheath cells (T. Hirose, B.W. Scheithauer). These tumors are characterized by aggressive growth with an unfavorable outcome and may develop de novo or through malignant transformation of schwannomas, neurofibromas, or ganglioneuromas. MPNSTs are characterized by a rapid course and a poor prognosis. In this article, we reported cases of patients with malignant peripheral nerve tumors of the brachial plexus trunks and spinal localization.
恶性外周神经鞘瘤(MPNSTs)是起源于外周神经鞘细胞的软组织肉瘤(T. Hirose,B.W. Scheithauer)。这些肿瘤的特点是生长迅速且预后不良,可原发发生,也可由神经鞘瘤、神经纤维瘤或神经节神经瘤恶变而来。MPNSTs病程进展迅速,预后较差。在本文中,我们报告了臂丛神经干和脊柱部位恶性外周神经肿瘤患者的病例。