Unidad de Ictus, Servicio de Neurología, Hospital Universitario Miguel Servet, Zaragoza, España; Instituto de Investigación Sanitaria (IIS), Aragón, Zaragoza, España.
Unidad de Ictus, Servicio de Neurología, Hospital Universitario Miguel Servet, Zaragoza, España.
Neurologia (Engl Ed). 2022 Jul-Aug;37(6):434-440. doi: 10.1016/j.nrl.2019.05.008. Epub 2019 Jul 21.
Stroke affects around 15 million people per year, with 10%-15% occurring in individuals under 50 years old (stroke in young adults). The prevalence of different vascular risk factors and healthcare strategies for stroke management vary worldwide, making the epidemiology and specific characteristics of stroke in each region an important area of research. This study aimed to determine the prevalence of different vascular risk factors and the aetiology and characteristics of ischaemic stroke in young adults in the autonomous community of Aragon, Spain.
A cross-sectional, multi-centre study was conducted by the neurology departments of all hospitals in the Aragonese Health Service. We identified all patients aged between 18 and 50 years who were admitted to any of these hospitals with a diagnosis of ischaemic stroke or TIA between January 2005 and December 2015. Data were collected on demographic variables, vascular risk factors, and type of stroke, among other variables.
During the study period, 786 patients between 18 and 50 years old were admitted with a diagnosis of ischaemic stroke or TIA to any hospital of Aragon, at a mean annual rate of 12.3 per 100 000 population. The median age was 45 years (IQR: 40-48 years). The most prevalent vascular risk factor was tobacco use, in 404 patients (51.4%). The majority of strokes were of undetermined cause (36.2%), followed by other causes (26.5%). The median NIHSS score was 3.5 (IQR: 2.0-7.0). In total, 211 patients (26.8%) presented TIA. Fifty-nine per cent of the patients admitted with a diagnosis of ischaemic stroke (10.3%) were treated with fibrinolysis.
Ischaemic stroke in young adults is not uncommon in Aragon, and is of undetermined aetiology in a considerable number of cases; it is therefore necessary to implement measures to improve study of the condition, to reduce its incidence, and to prevent its recurrence.
每年有 1500 万人受到中风的影响，其中 10%-15%发生在 50 岁以下的人群（青年中风）。不同血管危险因素的流行情况以及世界各地管理中风的医疗保健策略存在差异，使得每个地区中风的流行病学和具体特征成为一个重要的研究领域。本研究旨在确定西班牙阿拉贡自治区青年人群中不同血管危险因素的流行情况，以及缺血性中风的病因和特征。
由阿拉贡卫生服务系统所有医院的神经病学部门进行了一项横断面、多中心研究。我们确定了 2005 年 1 月至 2015 年 12 月期间在这些医院因缺血性中风或 TIA 入院的所有年龄在 18 至 50 岁之间的患者。收集了人口统计学变量、血管危险因素和中风类型等变量的数据。
在研究期间，786 名年龄在 18 至 50 岁之间的患者因缺血性中风或 TIA 被诊断为任何一家阿拉贡医院的患者，平均每年每 100000 人口中有 12.3 人。中位年龄为 45 岁（IQR：40-48 岁）。最常见的血管危险因素是吸烟，有 404 名患者（51.4%）。大多数中风的病因不明（36.2%），其次是其他病因（26.5%）。NIHSS 评分中位数为 3.5（IQR：2.0-7.0）。共有 211 名患者（26.8%）出现 TIA。诊断为缺血性中风的患者中，59%（10.3%）接受了纤溶治疗。
青年人群中的缺血性中风在阿拉贡并不少见，而且在相当数量的病例中病因不明；因此，有必要采取措施改善对这种疾病的研究，降低其发病率，并预防其复发。
