School of Nursing, Jilin University, Changchun, Jilin province, China.
Equal contributors.
West J Nurs Res. 2020 Jun;42(6):437-445. doi: 10.1177/0193945919866475. Epub 2019 Jul 25.
This study aimed to identify symptom clusters of chronic obstructive pulmonary disease (COPD) and to examine the relationship between symptom clusters and health-related quality of life (HRQoL). It included 154 hospitalized patients with COPD. The majority of the participants (88.6%) were aged 60 years and above, and the numbers of men and women were approximately equal (men: 55.2%). The Charlson Comorbidity Index (CCI), the Memorial Symptom Assessment Scale (MSAS), and the Chinese version of the Clinical COPD Questionnaire (CCQ) were used to evaluate comorbidity, participant's symptoms, and HRQoL, respectively. Five symptom clusters were identified using exploratory factor analysis, and symptom clusters, especially the Psychological, Pain and Fatigue, GI, and Dyspnea-Sweat symptom clusters, had negative effects on HRQoL in patients with COPD. Understanding the patterns and occurrences of symptom clusters could be essential for developing effective interventions to manage COPD symptoms and improve the patients' HRQoL.
本研究旨在确定慢性阻塞性肺疾病（COPD）的症状群，并探讨症状群与健康相关生活质量（HRQoL）之间的关系。共纳入 154 例住院 COPD 患者。大多数参与者（88.6%）年龄在 60 岁及以上，男女比例大致相等（男性：55.2%）。采用 Charlson 合并症指数（CCI）、纪念症状评估量表（MSAS）和中文版临床 COPD 问卷（CCQ）分别评估合并症、患者症状和 HRQoL。采用探索性因子分析确定了五个症状群，并且症状群，特别是心理、疼痛和疲劳、胃肠道和呼吸困难-出汗症状群，对 COPD 患者的 HRQoL 有负面影响。了解症状群的模式和发生情况对于制定有效的干预措施来管理 COPD 症状和提高患者的 HRQoL 至关重要。
