Moorfields Eye Hospital, London, United Kingdom; The Royal Victorian Eye and Ear Hospital, Melbourne, Australia.
Moorfields Eye Hospital, London, United Kingdom.
J AAPOS. 2019 Oct;23(5):252.e1-252.e4. doi: 10.1016/j.jaapos.2019.04.010. Epub 2019 Jul 22.
To determine the extent of superior oblique enlargement in thyroid eye disease (TED) by comparing the cross-sectional superior oblique areas of TED patients with those of unaffected control subjects.
The medical records of TED patients treated for strabismus from January 2005 to January 2016 were reviewed retrospectively for demographic and surgical data. The cross-sectional superior oblique area was compared to age-matched controls on high-resolution orbital computed tomography (CT) using a standardized protocol.
A total of 46 TED patients and 18 controls were included. The mean superior oblique cross-sectional area in TED subjects was 250% larger than in controls (22.88 ± 6.64 mm vs 9.32 ± 1.85 mm. The mean cross-sectional area was >3 standard deviations from the mean of the control group in 96% of TED patients.
Superior oblique enlargement in TED may occur more frequently than generally recognized, challenging the notion that TED is primarily a disease of the rectus muscles.
通过比较甲状腺眼病（TED）患者和无影响对照者的横向性上斜肌面积，确定 TED 中横向性上斜肌增大的程度。
回顾性分析了 2005 年 1 月至 2016 年 1 月期间因斜视接受治疗的 TED 患者的病历资料，以获取人口统计学和手术数据。使用标准化方案，在高分辨率眼眶 CT 上比较横向性上斜肌面积与年龄匹配的对照者。
共纳入 46 例 TED 患者和 18 例对照者。TED 患者的横向性上斜肌面积平均比对照组大 250%（22.88±6.64mm 比 9.32±1.85mm）。96%的 TED 患者的横向面积超过对照组平均值的 3 个标准差。
TED 中的横向性上斜肌增大可能比普遍认为的更为常见，这对 TED 主要是直肌疾病的观点提出了挑战。
