Department of Internal Medicine, Einstein Medical Center Philadelphia, PA.
Department of Digestive Diseases and Transplantation, Einstein Medical Center Philadelphia, PA.
Rev Cardiovasc Med. 2019 Jun 30;20(2):53-58. doi: 10.31083/j.rcm.2019.02.55.
Peripartum cardiomyopathy is a type of non-ischemic cardiomyopathy with a high rate of thromboembolic events. Guiding strategies for anticoagulation in patients with peripartum cardiomyopathy and thromboembolic events are limited. Literature for all cases of peripartum cardiomyopathy with intracardiac thrombi were reviewed and summarized from twelve case reports. Based on the available literature, we conclude that patients with peripartum cardiomyopathy with ejection fraction of less than 30% should strongly consider anticoagulation therapy to avoid thromboembolic events. Future studies may be able to further elucidate the optimal indication and duration of anticoagulation.
围生期心肌病是一种非缺血性心肌病，血栓栓塞事件发生率较高。围生期心肌病合并血栓栓塞事件患者的抗凝治疗指导策略有限。从 12 份病例报告中对所有围生期心肌病合并心内血栓形成的病例进行了文献复习和总结。基于现有文献，我们得出结论，射血分数小于 30%的围生期心肌病患者应强烈考虑抗凝治疗，以避免血栓栓塞事件。未来的研究可能能够进一步阐明抗凝治疗的最佳适应证和持续时间。
