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甲状腺全切除术:一项危险的手术?

Completion thyroidectomy: A risky undertaking?

机构信息

Division of Endocrine Surgery, Department of Surgery, University of Pittsburgh Medical Center, Kaufmann Building, Suite 101, 3471 Fifth Avenue, Pittsburgh, PA, 15213, United States.

出版信息

Am J Surg. 2019 Oct;218(4):695-699. doi: 10.1016/j.amjsurg.2019.07.014. Epub 2019 Jul 18.

Abstract

BACKGROUND

Completion thyroidectomy (cT) is sometimes necessary after thyroid lobectomy (TL), and it remains controversial whether 2-stage thyroidectomy adds operative risk. This study compares complication rates for TL, total thyroidectomy (TT), and cT.

METHODS

Using a cohort design, we reviewed 100 consecutive cases each of TL, TT, and cT. Complications examined included reoperation for hematoma, temporary/permanent recurrent laryngeal nerve (RLN) dysfunction, and hypoparathyroidism.

RESULTS

Two patients had reoperation for hematoma, both in the TT cohort (p = 0.33). No patients in any cohort had permanent hypoparathyroidism or RLN injury, but transient RLN paresis occurred in three (3%) TL, two (2%) TT, and no (0%) cT patients (p = 0.38). Transient hypoparathyroidism occurred in 3% following TT versus 0% after cT (p = 0.12). Overall complication rate was higher after TT (7%) compared to TL (3%) and cT (0%, p = 0.02).

CONCLUSIONS

At a high-volume center, the observed complication rates were equivalently low for TL, TT, and cT.

SUMMARY

Completion thyroidectomy is occasionally needed after lobectomy, but its procedure-specific risks are not well characterized. In a cohort study at a high-volume center, operative outcomes for patients undergoing thyroid lobectomy, total thyroidectomy, and completion thyroidectomy were compared and equivalently low complication rates were observed for all 3 procedures.

摘要

背景

甲状腺叶切除术后(TL)有时需要完成甲状腺切除术(cT),而两阶段甲状腺切除术是否会增加手术风险仍存在争议。本研究比较了 TL、全甲状腺切除术(TT)和 cT 的并发症发生率。

方法

使用队列设计,我们回顾了 100 例连续的 TL、TT 和 cT 病例。检查的并发症包括血肿的再次手术、暂时性/永久性喉返神经(RLN)功能障碍和甲状旁腺功能减退症。

结果

有 2 例患者因血肿而再次手术,均在 TT 组(p=0.33)。任何组均无永久性甲状旁腺功能减退症或 RLN 损伤,但 3 例(3%)TL、2 例(2%)TT 和无(0%)cT 患者出现暂时性 RLN 瘫痪(p=0.38)。TT 后出现暂时性甲状旁腺功能减退症的发生率为 3%,而 cT 后为 0%(p=0.12)。总的并发症发生率 TT 高于 TL(7%)和 cT(0%)(p=0.02)。

结论

在高容量中心,TL、TT 和 cT 的观察到的并发症发生率同样较低。

总结

甲状腺叶切除术后偶尔需要进行完成甲状腺切除术,但其特定手术风险尚未得到很好的描述。在一个高容量中心的队列研究中,比较了接受甲状腺叶切除术、全甲状腺切除术和完成甲状腺切除术的患者的手术结果,所有 3 种手术的并发症发生率均较低。

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