Rees R G, Ryan J, Attrill H A, Silk D B
Department of Gastroenterology & Nutrition, Central Middlesex Hospital, London, England.
JPEN J Parenter Enteral Nutr. 1988 May-Jun;12(3):274-7. doi: 10.1177/0148607188012003274.
Following a recent study in our Unit which showed that significantly more of prescribed enteral diet was administered from 2-liter bags than 0.51 bottles, a controlled clinical trial was undertaken to investigate further the effectiveness of the 2-liter prepackaged enteral delivery system. Forty patients with normal gastrointestinal function requiring enteral nutrition were randomized to receive nasogastrically 2-liter/day of polymeric diet (2000 kcal, 12 g N) either from a presterilized 2-liter PVC bag (Express EFI Ltd, UK) or from two 1-liter rigid plastic containers filled with cans of Clinifeed 400 (Roussel Laboratories Ltd, UK). The actual volumes of feed infused were monitored in patients fed for 5 days or more. Both nursing and dietetic staff preferred the 2-liter bags which were more convenient to prepare and use. Significantly larger quantities of prescribed diet were delivered from the 2-liter bags than from the 1-liter containers (p less than 0.001). It was concluded that the 2-liter bag system was potentially more convenient and nutritionally efficacious than 1-liter containers. Although the incidence of microbial contamination associated with the 2-liter bags was low, measures to maintain the sterility of this system may need to be more stringent.
我们科室最近的一项研究表明，从2升袋中给予的肠内营养处方量显著多于0.5升瓶，随后进行了一项对照临床试验，以进一步研究2升预包装肠内输送系统的有效性。40例需要肠内营养且胃肠功能正常的患者被随机分为两组，分别通过鼻胃管每天接受2升的聚合物饮食（2000千卡，12克氮），一组使用预先灭菌的2升聚氯乙烯袋（英国Express EFI有限公司），另一组使用两个装有Clinifeed 400罐装食品的1升刚性塑料容器（英国Roussel实验室有限公司）。对喂养5天或更长时间的患者输注的实际喂养量进行监测。护理人员和营养师都更喜欢2升袋，因为其制备和使用更方便。从2升袋中输送的处方饮食量明显多于1升容器（p<0.001）。得出的结论是，2升袋系统可能比1升容器更方便且营养效果更好。尽管与2升袋相关的微生物污染发生率较低，但可能需要采取更严格的措施来维持该系统的无菌状态。
