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医学虚无主义:对医学去情境化批判的局限性。

Medical nihilism: The limits of a decontextualised critique of medicine.

作者信息

Devanesan Arjun

机构信息

St Bartholomew's Hospital, West Smithfield, London, EC1A 7BE, UK.

出版信息

Stud Hist Philos Biol Biomed Sci. 2020 Feb;79:101189. doi: 10.1016/j.shpsc.2019.101189. Epub 2019 Jul 22.

Abstract

In a new and interesting book entitled Medical Nihilism (2018), Jacob Stegenga attempts to convince us that modern medical therapies are less effective than we think. Given the heterogeneity of hypotheses in medicine and the evidence for or against them, I argue that such a decontextualised critique cannot be made unless substantially weakened. Instead, I put forward an alternative, more nuanced and defensible epistemic view of medicine. According to this view, evaluating medical evidence requires analysis of both the methods of research e.g. randomised controlled trial (RCT), and context-specific information. This is because the way a trial (even an RCT) is conducted e.g. the population recruited and how it is intervened on, will vary and will have significant effects on the likelihood of a positive outcome. Moreover, the relationship between the positive outcome of a trial and the actual effectiveness of an intervention (the trial validity) will depend on these context specific factors. I argue for this position against nihilism by showing how each of Stegenga's individual claims about medical trials (trials are biased in favour of positive outcomes etc) can be questioned by taking the context into consideration.

摘要

在一本名为《医学虚无主义》(2018年)的新颖有趣的书中,雅各布·斯特根加试图让我们相信,现代医学疗法的效果不如我们想象的那么好。鉴于医学中假设的异质性以及支持或反对这些假设的证据,我认为,除非大幅弱化,否则无法进行这种脱离背景的批判。相反,我提出了一种关于医学的替代性、更细致入微且更具辩护力的认识论观点。根据这种观点,评估医学证据需要分析研究方法(例如随机对照试验)以及特定背景信息。这是因为进行试验(即使是随机对照试验)的方式,例如所招募的人群以及对其进行干预的方式,会有所不同,并且会对产生积极结果的可能性产生重大影响。此外,试验的积极结果与干预措施的实际效果之间的关系(试验效度)将取决于这些特定背景因素。我通过展示如何通过考虑背景来质疑斯特根加关于医学试验的每一项个人主张(试验偏向于积极结果等)来论证这一反对虚无主义的立场。

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