Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Head Neck. 2019 Oct;41(10):3677-3683. doi: 10.1002/hed.25884. Epub 2019 Jul 26.
Postoperative hypocalcemia (PH) is a serious complication after total thyroidectomy. This study aimed to compare PH rates between LigaSure Small Jaw (LSJ) and clamp-and-tie hemostatic technique in patients undergoing total thyroidectomy.
Four hundred twenty patients were divided into two groups: group L (210 patients) performed with LSJ and group C (210 patients) with clamp-and-tie technique. Serum ionized calcium (iCa) was measured before and 12, 24, 48, 72 hours after surgery. PH was defined as iCa lower than 4.2 mg/dL in at least two measurements.
There was no significant difference between groups in sex, age, extent of surgery, pathology, and the strategy of intraoperative management of parathyroid glands (PG). The PH rate was significantly lower in group L compared to group C (22.9% vs 32.4%, P = .03).
Compared to clamp-and-tie technique, LigaSure is superior to decrease PH rate after total thyroidectomy.
术后低钙血症（PH）是甲状腺全切除术后的一种严重并发症。本研究旨在比较 LigaSure Small Jaw（LSJ）与夹闭结扎止血技术在甲状腺全切除术中 PH 发生率的差异。
420 例患者分为两组：LSJ 组（210 例）和夹闭结扎组（210 例）。分别于术前、术后 12、24、48、72 小时测量血清离子钙（iCa）。PH 定义为至少两次测量 iCa 值低于 4.2mg/dL。
两组间性别、年龄、手术范围、病理、甲状旁腺（PG）术中处理策略无显著差异。LSJ 组 PH 发生率明显低于夹闭结扎组（22.9%比 32.4%，P=0.03）。
与夹闭结扎技术相比，LigaSure 可降低甲状腺全切除术后 PH 发生率。
