动态 FET PET 成像在“蝴蝶”型 IDH 野生型间变性星形细胞瘤中的应用。
Dynamic FET PET Imaging of a "Butterfly" IDH-Wildtype Anaplastic Astrocytoma.
机构信息
From the Department of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne.
Institute of Neuroscience and Medicine, Research Center Jülich, Jülich, Germany.
出版信息
Clin Nucl Med. 2019 Oct;44(10):e581-e582. doi: 10.1097/RLU.0000000000002740.
A variety of neoplastic and nonneoplastic conditions involve the corpus callosum, which may result in a "butterfly" appearance on conventional MRI. Typically, that pattern shows a bilateral and heterogeneous contrast enhancement of the lesion, occasionally with central nonenhancing areas indicating intralesional necrosis. In contrast, anaplastic gliomas may show only minimal or even a lack of contrast enhancement on MRI. We here report neuroimaging findings in a 69-year-old man with a "butterfly" pattern on dynamic FET [O-(2-[F]-fluoroethyl)-L-tyrosine] PET and the diagnosis of an anaplastic astrocytoma (WHO grade III; IDH-1/-2 wildtype, no 1p/19q co-deletion) but without typical MRI contrast enhancement.
多种肿瘤性和非肿瘤性病变累及胼胝体，这可能导致常规 MRI 呈现“蝴蝶”样外观。通常，这种模式表现为病变的双侧和不均匀对比增强，偶尔伴有中央无增强区，提示瘤内坏死。相比之下，间变性神经胶质瘤在 MRI 上可能仅表现为轻微增强，甚至无增强。我们在此报告一例 69 岁男性的神经影像学表现，该患者的动态 FET[O-(2-[F]-氟乙基)-L-酪氨酸]PET 呈现“蝴蝶”样模式，诊断为间变性星形细胞瘤（WHO 分级 III；IDH-1/-2 野生型，无 1p/19q 共缺失），但没有典型的 MRI 对比增强。
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