From the Institute of Nuclear Medicine and Molecular Imaging.
Departments of Radiology.
Clin Nucl Med. 2019 Oct;44(10):815-817. doi: 10.1097/RLU.0000000000002746.
Ga-DOTATATE imaging is commonly used for the detection of metastatic disease in neuroendocrine tumors. We present a case of a 69-year-old woman postsurgery for lung carcinoid tumor in which sequential follow-up Ga-DOTATATE PET/CT studies identified focal hepatic uptake that was presumed to represent a liver metastasis. However, correlative imaging with MRI revealed a focal fatty sparing of the liver composed of benign hepatic parenchyma at that area accompanied with diffuse liver steatosis in the background of the "pseudolesion." This report demonstrates a potential "false-positive" hepatic finding that can strikingly mimic a metastasis in neuroendocrine tumor imaging.
镓-DOTATATE 成像通常用于检测神经内分泌肿瘤的转移疾病。我们报告了一例 69 岁女性，术后患有肺类癌肿瘤，连续的 Ga-DOTATATE PET/CT 研究发现肝脏摄取局灶性，推测为肝转移。然而，与 MRI 的相关成像显示肝脏局灶性脂肪保留，该区域良性肝实质组成，背景为弥漫性肝脂肪变性的“假病变”。本报告表明了一种潜在的“假阳性”肝发现，在神经内分泌肿瘤成像中可以明显模拟转移。
