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急性一氧化碳中毒继发于 40 岁男性吸烟:病例报告。

Acute Carbon Monoxide Poisoning Secondary to Cigarette Smoking in a 40-Year-Old Man: A Case Report.

机构信息

Department of Psychiatry, University of Nebraska Medical Center, Omaha, Nebraska.

出版信息

Am J Addict. 2019 Sep;28(5):413-415. doi: 10.1111/ajad.12939. Epub 2019 Jul 26.

Abstract

BACKGROUND AND OBJECTIVES

Carbon monoxide is one of the most common causes of fatal intoxications in the United States, and multiple previous studies have demonstrated that cigarette smokers have higher levels of carbon monoxide in their blood. However, the potential negative effects due to acute carbon monoxide poisoning from excessive cigarette smoking have not been well established.

METHODS

This is a single patient case report.

RESULTS

In this case report, a 40-year-old male with a past medical history of depression, anxiety, panic attacks, and substance use disorder developed symptomatic, acute carbon monoxide poisoning secondary to heavy cigarette smoking in a confined space. In this patient, the cessation of clonazepam therapy coincided with increasing anxiety and panic disorder with agoraphobia triggering an escalation in his cigarette smoking. The patient smoked three packs of cigarettes in 3 hours and developed worsening of his symptoms. He required inpatient treatment with benzodiazepines and hyperbaric oxygen.

DISCUSSION AND CONCLUSIONS

Therefore, it is important to recognize cigarette smoke as a significant source of carbon monoxide exposure.

SCIENTIFIC SIGNIFICANCE

While the negative effects of cigarette smoking are often perceived as being chronic and only coming to fruition after numerous years of exposure, it is important for both physicians and patients to recognize the possibility for potentially life-threatening acute toxicity secondary to carbon monoxide exposure. (Am J Addict 2019;28:413-415).

摘要

背景与目的

一氧化碳在美国是最常见的致命中毒原因之一,多项先前的研究表明,吸烟者血液中的一氧化碳含量更高。然而,由于过量吸烟导致的急性一氧化碳中毒的潜在负面影响尚未得到充分证实。

方法

这是一份单一患者病例报告。

结果

在这个病例报告中,一名 40 岁的男性,既往有抑郁症、焦虑症、惊恐发作和物质使用障碍病史,在一个封闭空间中因大量吸烟而发生症状性、急性一氧化碳中毒。在该患者中,苯二氮䓬类药物治疗的停止恰逢焦虑和惊恐障碍的增加,伴广场恐怖症,从而导致其吸烟量增加。患者在 3 小时内吸了三包烟,症状恶化。他需要接受苯二氮䓬类药物和高压氧的住院治疗。

讨论与结论

因此,认识到香烟烟雾是一氧化碳暴露的一个重要来源非常重要。

科学意义

虽然吸烟的负面影响通常被认为是慢性的,只有在多年暴露后才会显现,但医生和患者都有必要认识到可能因接触一氧化碳而导致潜在危及生命的急性毒性的可能性。

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