From the Departments of Radiology (A.C.P., A.M.V.) and Urology (T.C.H., R.M.S.), University of California San Diego, San Diego, Calif, and Department of Radiology, University of North Carolina School of Medicine, Chapel Hill, NC (A.J.I.).
Radiographics. 2019 Sep-Oct;39(5):1526-1548. doi: 10.1148/rg.2019180195. Epub 2019 Jul 26.
Symptomatic benign prostatic hyperplasia is a common condition in the aging population that results in bothersome lower urinary tract symptoms and decreased quality of life. Patients often are treated with medication and offered surgery for persistent symptoms. Transurethral resection of the prostate is considered the traditional standard of care, but several minimally invasive surgical treatments also are offered. Prostatic artery embolization (PAE) is emerging as an effective treatment option with few reported adverse effects, minimal blood loss, and infrequent overnight hospitalization. The procedure is offered to patients with moderate to severe lower urinary tract symptoms and depressed urinary flow due to bladder outlet obstruction. Proper patient selection and meticulous embolization are critical to optimize results. To perform PAE safely and avoid nontarget embolization, interventional radiologists must have a detailed understanding of the pelvic arterial anatomy. Although the prostatic arteries often arise from the internal pudendal arteries, several anatomic variants and pelvic anastomoses are encountered. Prospective cohort studies, small randomized controlled trials, and meta-analyses have shown improved symptoms after treatment, with serious adverse effects occurring rarely. This article reviews the basic principles of PAE that must be understood to develop a thriving PAE practice. These principles include patient evaluation, review of surgical therapies, details of pelvic arterial anatomy, basic principles of embolization, and an overview of published results. RSNA, 2019.
症状性良性前列腺增生是老年人群中的一种常见疾病,会导致恼人的下尿路症状和生活质量下降。患者常因持续症状而接受药物治疗和手术治疗。经尿道前列腺切除术被认为是传统的标准治疗方法,但也提供了几种微创外科治疗方法。前列腺动脉栓塞术(PAE)作为一种有效的治疗选择,具有较少的不良反应、较少的失血和较少的夜间住院,越来越受到关注。该手术适用于因膀胱出口梗阻而出现中重度下尿路症状和尿流减少的患者。正确的患者选择和细致的栓塞是优化结果的关键。为了安全地进行 PAE 并避免非靶向栓塞,介入放射科医生必须详细了解盆腔动脉解剖结构。尽管前列腺动脉通常起源于阴部内动脉,但会遇到几种解剖变异和盆腔吻合。前瞻性队列研究、小型随机对照试验和荟萃分析表明,治疗后症状有所改善,严重不良事件很少发生。本文回顾了 PAE 的基本原则,这些原则必须被理解,以发展一个蓬勃发展的 PAE 实践。这些原则包括患者评估、手术治疗的回顾、盆腔动脉解剖的详细信息、栓塞的基本原理以及已发表结果的概述。RSNA,2019 年。