The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York.
The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York.
J Am Acad Dermatol. 2019 Dec;81(6):1387-1396. doi: 10.1016/j.jaad.2019.07.055. Epub 2019 Jul 23.
Vulvar malignancies represent a serious gynecologic health concern, especially given the increasing incidence over the past several decades. Squamous cell carcinoma and melanoma are common subtypes, although other neoplasms, such as basal cell carcinoma and Paget disease of the vulva, might be seen. Many vulvar cancers are initially misdiagnosed as inflammatory conditions, delaying diagnosis and worsening prognosis. It is essential that dermatologists are familiar with characteristic findings for each malignancy to ensure appropriate diagnosis and management. Herein, we review the unique epidemiologic and clinical characteristics of each major vulvar malignancy, as well as discuss their respective prognoses and current management recommendations.
外阴恶性肿瘤是一个严重的妇科健康问题,特别是在过去几十年中发病率不断增加的情况下。鳞状细胞癌和黑色素瘤是常见的亚型,尽管基底细胞癌和外阴派杰病等其他肿瘤也可能出现。许多外阴癌最初被误诊为炎症性疾病,导致诊断延误和预后恶化。皮肤科医生必须熟悉每种恶性肿瘤的特征表现,以确保做出正确的诊断和治疗。本文综述了每种主要外阴恶性肿瘤的独特流行病学和临床特征,并讨论了它们各自的预后和当前的治疗建议。