Department of Cardiothoracic Surgery, Weill Cornell Medicine, 5252 East 68th Street, New York, NY, 10065, USA.
Columbia University Vagelos College of Physicians and Surgeons, 3959 Broadway, CHN-270, New York, NY, 10032, USA.
Curr Cardiol Rep. 2019 Jul 27;21(9):99. doi: 10.1007/s11886-019-1195-8.
Aortic coarctation is a common congenital abnormality causing significant morbidity and mortality if not corrected. Re-coarctation or restenosis of the aorta following treatment is a relatively common long-term problem and the optimal therapy has not been elucidated. In this review, we identify the challenges associated with and the optimal management for recurrent aortic coarctation and the most appropriate therapy for different patient cohorts.
Open surgery provides a durable long-term aortic repair, however, given the complex nature of the procedure, has a somewhat higher rate of serious complications. Endovascular repair, although less invasive and relatively safe, has limitations in treated complex anatomy and is more likely to require repeat intervention. Open surgical repair is more appropriate for infants that have not been intervened on and endovascular therapy should be reserved for older children and adults and those that require repeat intervention.
主动脉缩窄是一种常见的先天性异常,如果不治疗会导致严重的发病率和死亡率。主动脉缩窄治疗后再狭窄或再狭窄是一个相对常见的长期问题,其最佳治疗方法尚未阐明。在这篇综述中,我们确定了与复发性主动脉缩窄相关的挑战以及最佳管理方法,并为不同的患者群体确定了最合适的治疗方法。
开放手术为主动脉提供了持久的长期修复,但由于手术的复杂性,严重并发症的发生率略高。虽然血管内修复创伤较小,相对安全,但在处理复杂解剖结构方面存在局限性,且更有可能需要重复干预。开放性手术修复更适用于未接受介入治疗的婴儿,而血管内治疗应保留给年龄较大的儿童和成人以及需要重复干预的患者。