York Health Economics Consortium, Enterprise House, Innovation Way, University of York , York, UK.
Diadem Medical Practice, Modality Partnership, NHS , Hull, UK.
Expert Rev Pharmacoecon Outcomes Res. 2020 Aug;20(4):387-395. doi: 10.1080/14737167.2019.1650024. Epub 2019 Aug 20.
People with diabetes are at increased risk of developing chronic kidney disease (CKD) and should undergo annual screening, but adherence is poor. A home urinalysis self-test has been developed to improve compliance with screening. The objective of this paper is to report on a clinical evaluation and economic analysis of home urinalysis self-testing.
People with diabetes who had not undergone screening within the previous 18 months were recruited to a single-arm clinical evaluation to assess the uptake and compliance of home urinalysis self-testing. An economic evaluation assessed the likely cost-consequences of the use of home urinalysis self-testing over a lifetime time horizon.
A total of 2,196 people with diabetes were contacted as part of the clinical evaluation. Of these, 695 people agreed to be sent a home urinalysis self-testing kit and 499 people completed and returned the test. Cost savings of £2,008 per person were estimated over a lifetime due to increased CKD diagnosis and reduced progression to end stage renal disease.
Home urinalysis self-testing of ACR in people with diabetes is estimated to be a cost-effective use of NHS resources in England in people who would otherwise not comply with standard care.
糖尿病患者发生慢性肾脏病（CKD）的风险增加，应每年进行筛查，但患者的依从性较差。现已研发出一种家用尿液分析自我检测法，以提高筛查的依从性。本文旨在报告家用尿液分析自我检测的临床评估和经济分析结果。
我们招募了未在过去 18 个月内接受过筛查的糖尿病患者，进行单臂临床评估，以评估家用尿液分析自我检测的参与度和依从性。经济评估评估了在终生时间范围内使用家用尿液分析自我检测的可能成本后果。
临床评估共联系了 2196 名糖尿病患者。其中，695 人同意寄发家用尿液分析自我检测试剂盒，499 人完成并返回了检测。由于 CKD 的诊断增加和进展为终末期肾病的减少，预计每个人的终生节省成本为 2008 英镑。
在英格兰，对于那些不符合标准护理的人来说，家用尿液分析自我检测 ACR 估计可有效利用国民保健制度资源，是一种具有成本效益的方法。
