Rejuvenation Res. 2019 Aug;22(4):353-358. doi: 10.1089/rej.2019.2248.
Theses reviewed in this issue include "Downregulation of the Apelinergic Axis Accelerates Aging, Whereas Its Systemic Restoration Improves the Mammalian Healthspan," "Intracellular Delivery of Exogenous Molecules Via an Ultrahigh Throughput Mechanoporation Microdevice," "Intrinsic and Extrinsic Drivers of Treg Fragility in the Tumor Microenvironment," "Lipid Nanoparticles Based Nanomedicine and Liquid Biopsy in Lung Cancer Therapy and Diagnosis," "Stimuli-Responsive Biomaterials for Drug Delivery to Improve Cancer Immunotherapy and Chronic Wound Healing," and "Zebrafish Extracellular Matrix as a Therapeutic Agent for Adult Mammalian Central Nervous System Regeneration."
本期评论包括“Apelin 轴的下调加速衰老,而其系统恢复可改善哺乳动物的健康寿命”、“通过高通量机械穿孔微器件细胞内递外源性分子”、“肿瘤微环境中 Treg 脆弱性的内在和外在驱动因素”、“基于脂质纳米颗粒的纳米医学和液体活检在肺癌治疗和诊断中的应用”、“用于改善癌症免疫治疗和慢性伤口愈合的药物递送至刺激响应生物材料”以及“斑马鱼细胞外基质作为治疗成年哺乳动物中枢神经系统再生的药物”。