Hammersley Gabrielle R, Nichol Meghan F, Steffens Helena C, Delgado Jose M, Veits Gesine K, Read de Alaniz Javier
Department of Chemistry and Biochemistry, University of California Santa Barbara, Santa Barbara, CA 93106-9510, USA.
Beilstein J Org Chem. 2019 Jul 12;15:1569-1574. doi: 10.3762/bjoc.15.160. eCollection 2019.
An enantioselective aza-Piancatelli rearrangement has been developed using a chiral Brønsted acid based on pentacarboxycyclopentadiene (PCCP). This reaction provides rapid access to valuable chiral 4-amino-2-cyclopentenone building blocks from readily available starting material and is operationally simple.
基于五羧基环戊二烯（PCCP）的手性布朗斯特酸已被用于开发对映选择性氮杂-Piancatelli重排反应。该反应能从易得的起始原料快速获得有价值的手性4-氨基-2-环戊烯酮结构单元，且操作简单。
