de Freitas Filho Silas Antonio Juvencio, Garcia Natália Galvão, Chicrala Gabriela Moura, Santos Paulo Sérgio Silva, Oliveira Denise Tostes
Gen Dent. 2019 Jul-Aug;67(4):35-37.
Melanocytic nevi are acquired or congenital benign neoplasms, often found in skin but rarely in the oral mucosa. This article reports an atypical case of oral hypopigmented melanocytic nevus in a 39-year-old woman referred for evaluation of a well-circumscribed papule with discrete brownish spots in the buccal mucosa. An excisional biopsy was performed, the results of which led to a clinical diagnosis of inflammatory fibrous hyperplasia. The histopathologic analysis resulted in a diagnosis of hypopigmented intramucosal melanocytic nevus. This unusual clinical manifestation of melanocytic nevus reinforces the importance of including nonpigmented or hypopigmented melanocytic nevi in the differential diagnosis of papules arising in the oral mucosa. A biopsy and subsequent histologic examination of the specimen are recommended to establish an accurate diagnosis.
黑素细胞痣是后天获得性或先天性良性肿瘤，常见于皮肤，但很少见于口腔黏膜。本文报告了一例39岁女性口腔色素减退性黑素细胞痣的非典型病例，该患者因颊黏膜出现边界清晰的丘疹伴散在褐色斑点而前来评估。进行了切除活检，结果临床诊断为炎性纤维增生。组织病理学分析诊断为黏膜内色素减退性黑素细胞痣。黑素细胞痣这种不寻常的临床表现强化了在口腔黏膜丘疹鉴别诊断中纳入无色素或色素减退性黑素细胞痣的重要性。建议进行活检及随后对标本进行组织学检查以明确准确诊断。
