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周围神经阻滞用于门诊肩部手术:一项基于人群的结局和资源利用的队列研究。

Peripheral Nerve Blocks for Ambulatory Shoulder Surgery: A Population-based Cohort Study of Outcomes and Resource Utilization.

机构信息

From the Department of Anesthesiology and Pain Medicine (G.M.H., R.R., A.L., C.J.L.M., F.A., J.M., D.I.M.) School of Epidemiology and Public Health (D.I.M.), University of Ottawa, Ottawa, Canada The Ottawa Hospital Research Institute, Ottawa, Canada (R.R., A.L., C.J.L.M., F.A., D.I.M.) the Institute for Clinical Evaluative Sciences (IC/ES), Toronto, Canada (D.I.M.).

出版信息

Anesthesiology. 2019 Dec;131(6):1254-1263. doi: 10.1097/ALN.0000000000002865.

Abstract

BACKGROUND

Nerve blocks improve early pain after ambulatory shoulder surgery; impact on postdischarge outcomes is poorly described. Our objective was to measure the association between nerve blocks and health system outcomes after ambulatory shoulder surgery.

METHODS

We conducted a population-based cohort study using linked administrative data from 118 hospitals in Ontario, Canada. Adults having elective ambulatory shoulder surgery (open or arthroscopic) from April 1, 2009, to December 31, 2016, were included. After validation of physician billing codes to identify nerve blocks, we used multilevel, multivariable regression to estimate the association of nerve blocks with a composite of unplanned admissions, emergency department visits, readmissions or death within 7 days of surgery (primary outcome) and healthcare costs (secondary outcome). Neurology consultations and nerve conduction studies were measured as safety indicators.

RESULTS

We included 59,644 patients; blocks were placed in 31,073 (52.1%). Billing codes accurately identified blocks (positive likelihood ratio 16.83, negative likelihood ratio 0.03). The composite outcome was not significantly different in patients with a block compared with those without (2,808 [9.0%] vs. 3,424 [12.0%]; adjusted odds ratio 0.96; 95% CI 0.89 to 1.03; P = 0.243). Healthcare costs were greater with a block (adjusted ratio of means 1.06; 95% CI 1.02 to 1.10; absolute increase $325; 95% CI $316 to $333; P = 0.005). Prespecified sensitivity analyses supported these results. Safety indicators were not different between groups.

CONCLUSIONS

In ambulatory shoulder surgery, nerve blocks were not associated with a significant difference in adverse postoperative outcomes. Costs were statistically higher with a block, but this increase is not likely clinically relevant.

摘要

背景

神经阻滞可改善门诊肩部手术后的早期疼痛;但其对出院后结果的影响描述得很差。我们的目的是测量在门诊肩部手术后,神经阻滞与卫生系统结果之间的关联。

方法

我们使用来自加拿大安大略省 118 家医院的链接行政数据进行了一项基于人群的队列研究。纳入 2009 年 4 月 1 日至 2016 年 12 月 31 日期间行择期门诊肩部手术(开放或关节镜)的成年人。在验证了医师计费代码以识别神经阻滞之后,我们使用多水平、多变量回归来估计神经阻滞与术后 7 天内非计划入院、急诊就诊、再入院或死亡的复合结果(主要结局)以及医疗保健费用(次要结局)之间的关联。神经科会诊和神经传导研究作为安全指标进行测量。

结果

我们纳入了 59644 名患者;其中 31073 名(52.1%)患者接受了阻滞。计费代码准确识别了阻滞(阳性似然比 16.83,阴性似然比 0.03)。与未接受阻滞的患者相比,接受阻滞的患者复合结局无显著差异(2808 例[9.0%]与 3424 例[12.0%];调整后的优势比 0.96;95%置信区间 0.89 至 1.03;P=0.243)。接受阻滞的患者医疗保健费用更高(调整后的均数比 1.06;95%置信区间 1.02 至 1.10;绝对增加 325 美元;95%置信区间 316 美元至 333 美元;P=0.005)。预设定的敏感性分析支持这些结果。两组之间的安全指标没有差异。

结论

在门诊肩部手术中,神经阻滞与术后不良结局无显著差异。虽然接受阻滞的患者费用统计上更高,但这种增加可能在临床上并不相关。

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