Sze G, Simmons B, Krol G, Walker R, Zimmerman R D, Deck M D
Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021.
AJNR Am J Neuroradiol. 1988 Jul-Aug;9(4):679-86.
Although MR imaging is being used increasingly to detect dural sinus thrombosis, accurate evaluation of images has often been hindered by the presence of artifacts, especially flow-related enhancement, that may simulate intraluminal clot. We tried an approach with spin-echo techniques to eliminate flow-induced artifacts and, thus, facilitate the diagnosis of dural sinus thrombosis. In this investigation, a nonselective single-section spin-echo verification method was used as a prototype of this approach. Both patients and an experimental flow phantom were used to test the validity of this concept. Clinically, thrombosis was seen to persist as isointense or highly intense signal in the vascular lumina with the specialized sequence, while flow-related artifacts were replaced by hypointense signal, but not by signal void. These same changes were examined both quantitatively and qualitatively in the flow phantom by using varying velocities of flow. Although our clinical investigation concerns suspected dural sinus thrombosis, the principles of these specialized spin-echo techniques can be applied successfully throughout the head to eliminate certain flow-related artifacts.
尽管磁共振成像（MR成像）越来越多地用于检测硬脑膜窦血栓形成，但图像的准确评估常常受到伪影的阻碍，尤其是与血流相关的强化，这可能会模拟管腔内血栓。我们尝试了一种利用自旋回波技术的方法来消除血流诱导的伪影，从而有助于硬脑膜窦血栓形成的诊断。在本研究中，一种非选择性单层面自旋回波验证方法被用作该方法的原型。患者和实验性血流模型均用于测试这一概念的有效性。临床上，在使用专门序列时，血栓在血管腔内表现为等信号或高信号，而与血流相关的伪影则被低信号取代，而非信号缺失。通过在血流模型中使用不同的血流速度，对这些相同的变化进行了定量和定性研究。尽管我们的临床研究关注疑似硬脑膜窦血栓形成，但这些专门的自旋回波技术的原理可以成功地应用于整个头部，以消除某些与血流相关的伪影。
