Soave Armin, Laurich Sebastian, Dahlem Roland, Vetterlein Malte W, Engel Oliver, Nieder Timo, Briken Peer, Rink Michael, Fisch Margit, Reiss Philip
Department of Urology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Institute for Sex Research, Sexual Medicine and Forensic Psychiatry, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
J Clin Med. 2019 Jul 28;8(8):1121. doi: 10.3390/jcm8081121.
To assess patient satisfaction with surgical outcome, body related self-perceptions, self-attitudes of sexuality, and health related quality of life after penile surgery with small intestinal submucosa (SIS) grafting for the treatment of severe Peyronie's disease (PD).
This retrospective study included 82 patients, who were treated with SIS grafting for severe PD between 2009 and 2013 at the University Medical Center Hamburg-Eppendorf. Patients were asked to complete standardized questionnaires including the International Index of Erectile Function Erectile Function domain (IIEF-EF), Short-Form (SF)-8 Health Survey, and Frankfurt Body Concept Scale-Sexuality (FKKS-SEX).
Follow-up was available in 58 (69.9%) patients. SIS grafting resulted in subjective straightening of the penis in 53 (91.3%) patients. After a mean follow-up of 28.9 ± 16.5 months, 24 (41.4%) patients were satisfied or very satisfied with surgical outcome. Postoperatively, the mean FKKS-SEX was 23.5 ± 5.9. In total, 36 (62.1%), 18 (31%), and four (6.9%) patients had FKKS-SEX scores corresponding to positive, neutral, and negative self-perception and self-attitude of sexuality, respectively. The mean postoperative SF-8 was 15.2 ± 6.4. Compared to the mean for German controls, patients achieved lower mean scores in the domains social functioning (50.4 ± 7.1), mental health (49.5 ± 9.2), and emotional roles (48.5 ± 6.8). Subjective shortening of the penis (Odds ratio (OR): 2.0), negative body related self-perceptions, and self-attitudes of sexuality (OR: 3.6) as well as IIEF-EF score (OR: 0.9) were risk factors for patient dissatisfaction (-values ≤ 0.02).
A relevant number of patients is not satisfied with surgical outcome after SIS grafting for the treatment of severe PD. Subjective shortening of the penis, negative body related self-perceptions, and self-attitudes of sexuality as well as IIEF-EF score were risk factors for patient dissatisfaction.
评估采用小肠黏膜下层(SIS)移植治疗重度佩罗尼氏病(PD)的阴茎手术后患者对手术效果的满意度、与身体相关的自我认知、性方面的自我态度以及与健康相关的生活质量。
这项回顾性研究纳入了82例患者,他们于2009年至2013年在汉堡 - 埃彭多夫大学医学中心接受了SIS移植治疗重度PD。患者被要求完成标准化问卷,包括国际勃起功能指数勃起功能领域(IIEF - EF)、简短形式(SF)-8健康调查以及法兰克福身体概念量表 - 性(FKKS - SEX)。
58例(69.9%)患者有随访数据。SIS移植使53例(91.3%)患者阴茎主观变直。平均随访28.9±16.5个月后,24例(41.4%)患者对手术效果满意或非常满意。术后,FKKS - SEX平均分为23.5±5.9。总体而言,分别有36例(62.1%)、18例(31%)和4例(6.9%)患者的FKKS - SEX评分对应性方面的积极、中性和消极自我认知及自我态度。术后SF - 8平均分为15.2±6.4。与德国对照组均值相比,患者在社会功能(50.4±7.1)、心理健康(49.5±9.2)和情感角色(48.5±6.8)领域的平均得分较低。阴茎主观缩短(优势比(OR):2.0)、与身体相关的消极自我认知和性方面的自我态度(OR:3.6)以及IIEF - EF评分(OR:0.9)是患者不满意的危险因素(P值≤0.02)。
相当数量的患者对采用SIS移植治疗重度PD的手术效果不满意。阴茎主观缩短、与身体相关的消极自我认知、性方面的自我态度以及IIEF - EF评分是患者不满意的危险因素。