Jiang Yahui, Jia Nan, Zhu Menghan, He Yuan, Che Xiaoxia, Lv Tianjiao, Feng Weiwei
Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.
Department of Gynecology and Obstetrics, Ruijin Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China.
J Int Med Res. 2019 Sep;47(9):4469-4481. doi: 10.1177/0300060519863190. Epub 2019 Jul 29.
We aimed to compare the survival and perioperative outcomes of patients with stage II endometrial cancer (EC) undergoing simple hysterectomy (SH) or radical hysterectomy (RH), to validate the various guidelines.
A total of 155 consecutive patients diagnosed with stage II EC from 2000 to 2014 were reviewed. We identified 40 pairs of patients (40 SH and 40 RH) who were matched in terms of age, pathological type, and lymphovascular space invasion status using matched-pair analysis. Patient data were collected from medical records and outcomes were determined by telephone follow-up.
Among the 80 patients in the two groups, seven died from tumor recurrence. However, cancer-related survival rates were not significantly different between the SH and RH groups. The 3-year cancer-related survival rates in the SH and RH groups were 94.97% and 92.53%, and the 5-year survival rates were 92.40% and 90.03%, respectively. Regarding perioperative outcomes, the SH group had significantly less intraoperative bleeding and a significantly shorter catheter-indwelling time than the RH group.
SH provides similar survival outcomes and a superior perioperative quality of life compared with RH in patients with stage II EC.
我们旨在比较接受单纯子宫切除术（SH）或根治性子宫切除术（RH）的II期子宫内膜癌（EC）患者的生存率和围手术期结局，以验证各种指南。
回顾了2000年至2014年期间连续诊断为II期EC的155例患者。我们使用配对分析确定了40对患者（40例SH和40例RH），这些患者在年龄、病理类型和淋巴血管间隙浸润状态方面相匹配。患者数据从病历中收集，结局通过电话随访确定。
两组80例患者中，7例死于肿瘤复发。然而，SH组和RH组的癌症相关生存率无显著差异。SH组和RH组的3年癌症相关生存率分别为94.97%和92.53%，5年生存率分别为92.40%和90.03%。关于围手术期结局，SH组术中出血量明显少于RH组，导尿管留置时间明显短于RH组。
对于II期EC患者，与RH相比，SH提供了相似的生存结局和更好的围手术期生活质量。
