Para-aminobenzoate inhibition of precipitation of urine salts.

Lehmann's observation that potassium para-aminobenzoate has a "salt precipitating preventive effect" in urine was confirmed in rats. This effect persisted during the 3-week period of drug administration. There was associated no significant change in urine volume, osmolality, or per cent solids. Since there is a large clinical experience in the chronic use of even larger doses, it would appear quite feasible to determine the clinical usefulness of this property of para-aminobenzoate in the prevention of recurrent renal calculi.