Department of Medicine, Epidemiology & Population Sciences, Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, One Baylor Plaza, MS: BCM307, Room 613D, Houston, TX, 77030, USA.
Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Curr Oncol Rep. 2019 Jul 29;21(9):80. doi: 10.1007/s11912-019-0829-8.
Malnutrition is a common and under-recognized geriatric condition in older adults with cancer. This review describes the public health burden, malnutrition prevention, and the relationship among cancer cachexia, malnutrition, and sarcopenia. Finally, clinical practice recommendations on malnutrition and prevention are presented.
Advanced age and cancer stage, frailty, dementia, major depression, functional impairment, and physical performance are important risk factors for malnutrition in older adults with cancer. The Mini Nutrition Assessment (MNA), Malnutrition Universal Screening Tool (MUST), and Patient Generated Subjective Global Assessment (PG-SGA) are the most commonly used assessment tools in older adults with cancer. In addition, malnutrition is independently associated with poor overall survival and quality of life, longer hospital stays, greater hospital cost, and hospital readmission. Comprehensive malnutrition prevention is required for improving the nutrition status among older adults with cancer.
营养不良是老年癌症患者中一种常见且未被充分认识的老年病。本文描述了营养不良的公共卫生负担、预防措施以及癌症恶病质、营养不良和肌肉减少症之间的关系。最后,提出了有关营养不良和预防的临床实践建议。
高龄和癌症分期、虚弱、痴呆、重度抑郁、功能障碍和身体机能是老年癌症患者营养不良的重要危险因素。在老年癌症患者中,最常用的评估工具是微型营养评估(MNA)、营养不良通用筛查工具(MUST)和患者主观整体评估(PG-SGA)。此外,营养不良与整体生存率和生活质量差、住院时间延长、住院费用增加和再住院率高独立相关。需要对老年癌症患者进行全面的营养不良预防,以改善其营养状况。