Delaire J, Tessier P, Tulasne J F, Resche F
Rev Stomatol Chir Maxillofac. 1979;80(2):68-82.
Maxillo-nasal dysostosis is not uncommon as we have noted 34 new cases in eight years. The most characteristic anomalies, well described by Binder, are nasal hypoplasia both of bone and cartilage with agenesis of the nasal spine, as well as a characteristic rearrangement of the naso-labial muscles. On first seeing the patient the disease is generally recognized by the very typical aspect of the nose. There very often exists however other dental, mandibular and cervical spine anomolies. It is indispensable to look for these anomalies in the work up of patients with this malformation syndrome "the naso-maxillo-vertebral syndrome", in order to better understand the disease and better treat the patients.
上颌鼻发育不全并不罕见，我们在八年里就记录了34例新病例。正如宾德所详细描述的，最典型的异常表现为鼻骨和鼻软骨发育不全、鼻棘缺失，以及鼻唇肌的特征性重新排列。初次见到患者时，该病通常可通过鼻子的典型外观得以识别。然而，患者常常还存在其他牙齿、下颌骨和颈椎异常。在对患有这种畸形综合征（“鼻上颌椎骨综合征”）的患者进行检查时，务必查找这些异常情况，以便更好地了解病情并为患者提供更有效的治疗。
