Kritmetapak Kittrawee, Dumrongsukit Sophon, Jinchai Jittirat, Wongprommek Panibud
Division of Nephrology, Faculty of Medicine Khon Kaen University Khon Kaen Thailand.
Department of Medicine, Faculty of Medicine Khon Kaen University Khon Kaen Thailand.
Clin Case Rep. 2019 Jun 14;7(7):1426-1429. doi: 10.1002/ccr3.2264. eCollection 2019 Jul.
Pseudohyperphosphatemia is a laboratory artifact characterized by falsely elevated serum phosphate mostly due to paraprotein interference on the conventional automated analyzer. Clinician recognition of this phenomenon and pre-analytical preparation, including dilution or protein precipitation, can obviate unnecessary therapy and potentially unveil the diagnosis of paraproteinemia especially related to multiple myeloma.
假性高磷血症是一种实验室假象,其特征是血清磷酸盐假性升高,主要是由于在传统自动分析仪上副蛋白的干扰所致。临床医生认识到这种现象并进行分析前准备,包括稀释或蛋白质沉淀,可以避免不必要的治疗,并有可能揭示尤其是与多发性骨髓瘤相关的副蛋白血症的诊断。