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丛状纤维黏液瘤的临床病理和分子特征的最新研究进展。

An Update on Clinicopathological and Molecular Features of Plexiform Fibromyxoma.

机构信息

Department of Medical Education, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.

Endoscopy Center, Changhua Christian Hospital, Changhua, Taiwan.

出版信息

Can J Gastroenterol Hepatol. 2019 Jul 7;2019:3960920. doi: 10.1155/2019/3960920. eCollection 2019.

DOI:10.1155/2019/3960920
PMID:31360694
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6642755/
Abstract

Plexiform fibromyxoma is a rare and newly described gastric mesenchymal tumor with only 121 reported cases in the literature. Our understanding of plexiform fibromyxoma requires updating since the first case has been reported by Takahashi et al. 12 years ago. The present review summarized reported cases in the literature, and both clinical and pathological aspects of plexiform fibromyxoma were comprehensively discussed. Plexiform fibromyxoma usually causes nonspecific or bleeding signs or symptoms, and therefore clinical recognition of the disease is challenging. Plexiform fibromyxoma is of benign nature without any metastasis or recurrence reported, and more conservative surgical treatment should be considered.

摘要

丛状纤维黏液瘤是一种罕见的、新描述的胃间叶性肿瘤,文献中仅报道了 121 例。自 Takahashi 等人 12 年前首次报道首例病例以来,我们对丛状纤维黏液瘤的认识需要更新。本综述总结了文献中的报道,并全面讨论了丛状纤维黏液瘤的临床和病理方面。丛状纤维黏液瘤通常导致非特异性或出血症状,因此临床识别该疾病具有挑战性。丛状纤维黏液瘤为良性,无转移或复发报道,应考虑更保守的手术治疗。

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本文引用的文献

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Plexiform fibromyxoma of the stomach: a clinicopathological study of 10 cases.胃丛状纤维黏液瘤:10例临床病理研究
Int J Clin Exp Pathol. 2017 Nov 1;10(11):10926-10933. eCollection 2017.
2
Smoothened-dependent and -independent pathways in mammalian noncanonical Hedgehog signaling.哺乳动物非经典 Hedgehog 信号通路中的 Smoothened 依赖性和非依赖性途径。
J Biol Chem. 2019 Jun 21;294(25):9787-9798. doi: 10.1074/jbc.RA119.007956. Epub 2019 Apr 16.
3
Gastric Plexiform Fibromyxoma: A Great Mimic of Gastrointestinal Stromal Tumor (GIST) and Diagnostic Pitfalls.胃丛状纤维黏液瘤:胃肠道间质瘤(GIST)的巨大“伪装者”及诊断陷阱。
J Surg Res. 2019 Jul;239:76-82. doi: 10.1016/j.jss.2019.01.062. Epub 2019 Feb 26.
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Gastric Plexiform Fibromyxoma.胃丛状纤维黏液瘤
J Gastrointest Surg. 2019 Sep;23(9):1936-1939. doi: 10.1007/s11605-019-04132-0. Epub 2019 Feb 13.
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Gastric plexiform fibromyxoma: A rare case in a 5-year-old male.胃丛状纤维黏液瘤:一名5岁男性的罕见病例。
Pediatr Blood Cancer. 2019 May;66(5):e27638. doi: 10.1002/pbc.27638. Epub 2019 Jan 29.
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Pediatric plexiform fibromyxoma: A PRISMA-compliant systematic literature review.小儿丛状纤维黏液瘤:一项符合PRISMA标准的系统文献综述。
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