放射科医生进阶：晚期非小细胞肺癌治疗模式的改变——2018 年美国临床肿瘤学会（ASCO）分子检测指南与靶向治疗
A Radiologist's Guide to the Changing Treatment Paradigm of Advanced Non-Small Cell Lung Cancer: The ASCO 2018 Molecular Testing Guidelines and Targeted Therapies.
机构信息
Department of Radiology, University Hospitals Cleveland Medical Center, 11100 Euclid Ave, Cleveland, OH 44106.
Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Boston, MA.
出版信息
AJR Am J Roentgenol. 2019 Nov;213(5):1047-1058. doi: 10.2214/AJR.19.21135. Epub 2019 Jul 30.
The purpose of this article is to provide an imaging-based guide of the modern genomic classifications and targeted therapies for advanced non-small cell lung cancer (NSCLC) with an emphasis on the relevance of the 2018 American Society of Clinical Oncology molecular testing guidelines for radiologists. Knowledge of the radiologic relevance of lung cancer driver mutations and modern targeted agents is essential for imaging interpretation of advanced NSCLC in the modern age of precision medicine.
本文旨在提供基于影像学的指导，介绍晚期非小细胞肺癌（NSCLC）的现代基因组分类和靶向治疗方法，重点介绍了 2018 年美国临床肿瘤学会分子检测指南对放射科医生的相关性。了解肺癌驱动基因突变和现代靶向药物的放射学相关性，对于精准医学时代晚期 NSCLC 的影像学解读至关重要。
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