Vavricka Stephan R, Greuter Thomas
Center of Gastroenterology and Hepatology, CH-8048 Zurich, Switzerland.
Department of Gastroenterology and Hepatology, University Hospital Zurich, CH-8091 Zurich, Switzerland.
J Clin Med. 2019 Jul 29;8(8):1127. doi: 10.3390/jcm8081127.
Gastroparesis and dumping syndrome both evolve from a disturbed gastric emptying mechanism. Although gastroparesis results from delayed gastric emptying and dumping syndrome from accelerated emptying of the stomach, the two entities share several similarities among which are an underestimated prevalence, considerable impairment of quality of life, the need for a multidisciplinary team setting, and a step-up treatment approach. In the following review, we will present an overview of the most important clinical aspects of gastroparesis and dumping syndrome including epidemiology, pathophysiology, presentation, and diagnostics. Finally, we highlight promising therapeutic options that might be available in the future.
胃轻瘫和倾倒综合征均源于胃排空机制紊乱。尽管胃轻瘫是由胃排空延迟引起的，而倾倒综合征是由胃排空加速导致的，但这两种病症有若干相似之处，包括患病率被低估、生活质量受到严重损害、需要多学科团队协作以及采用逐步升级的治疗方法。在以下综述中，我们将概述胃轻瘫和倾倒综合征最重要的临床方面，包括流行病学、病理生理学、临床表现和诊断。最后，我们强调未来可能会有的前景广阔的治疗选择。
