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以柯萨奇病毒B4感染和胆囊切除术后为先兆的晚期倾倒综合征。

Late dumping syndrome preceded by Coxsackievirus B4 infection and cholecystectomy.

作者信息

Weiss Joshua, Fewel Connor, Akinrinade Oyediran, Harrington Jane

机构信息

Department of Microbiology, St. George's University, School of Medicine, True Blue Campus, St. George, Grenada, West Indies.

出版信息

J Surg Case Rep. 2023 Apr 25;2023(4):rjad205. doi: 10.1093/jscr/rjad205. eCollection 2023 Apr.

Abstract

A 44-year-old female patient presented with weight loss, diarrhea and intermittent episodes of left upper quadrant (LUQ) pain lasting for 3 years, accompanied by acute episodes of focal LUQ pain, dizziness, tachycardia, borborygmi and bloating, occurring approximately 60 min after meals. The patient developed chronic acalculous cholecystitis and transient exocrine pancreatic insufficiency after infection with Coxsackievirus B4 (CVB4), which resolved following laparoscopic cholecystectomy 2 years before the current presentation. Although imaging and functional investigation studies were unremarkable, a gastric transit study revealed rapid clearance of radiolabeled food, and the patient's symptomatology and gastrointestinal studies supported the diagnosis of late dumping syndrome. The patient's symptoms significantly improved with adherence to recommended dietary changes, including an increase in protein intake, abstinence from simple carbohydrates and avoidance of simultaneous consumption of beverages with food, following consultation with a dietitian.

摘要

一名44岁女性患者出现体重减轻、腹泻以及左上腹(LUQ)间歇性疼痛3年,伴有餐后约60分钟出现的左上腹局部剧痛、头晕、心动过速、肠鸣音和腹胀等急性发作症状。该患者在感染柯萨奇病毒B4(CVB4)后出现慢性非结石性胆囊炎和短暂性外分泌性胰腺功能不全,在本次就诊前2年行腹腔镜胆囊切除术后症状缓解。尽管影像学和功能检查均无异常,但一项胃排空研究显示放射性标记食物清除迅速,患者的症状及胃肠道检查结果支持晚期倾倒综合征的诊断。在咨询营养师后,患者通过遵循推荐的饮食改变,包括增加蛋白质摄入量、戒除简单碳水化合物以及避免食物与饮料同时食用,症状得到显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fd6/10131098/93ecbd45af1b/rjad205f1.jpg

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