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老年人使用精神类药物组合与髋部骨折风险

Combination psychotropic medicine use in older adults and risk of hip fracture.

作者信息

Westaway Kerrie, Blacker Natalie, Shute Russell, Allin Rosemary, Elgebaly Zain, Frank Oliver, Pratt Nicole, Roughead Elizabeth

机构信息

Veterans' Medicines Advice and Therapeutics Education Services (Veterans' MATES) program, Adelaide.

Veterans' MATES Clinical Reference Group, Adelaide.

出版信息

Aust Prescr. 2019 Jun;42(3):93-96. doi: 10.18773/austprescr.2019.011. Epub 2019 Jun 3.

DOI:10.18773/austprescr.2019.011
PMID:31363307
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6594851/
Abstract

Older people might be embarrassed to talk about falling as they worry this may be judged as a loss of their ability to live independently. Ask older patients, at least yearly, if they ever feel unsteady on their feet or if they have fallen Consider whether medicines may be contributing to feelings of unsteadiness or falling. Drugs such as benzodiazepines and selective serotonin reuptake inhibitors, particularly if taken together, are associated with a risk of falling and hip fracture Review the patient’s treatment regimen to see if there are drugs that are no longer required. Psychotropic drugs should usually be tapered gradually so that adverse effects can be minimised Involve a range of health professionals to identify and manage the risk of falls. Help patients stay physically active, independent and socially connected

摘要

老年人可能会因担心这会被视为失去独立生活能力而不好意思谈论跌倒的问题。至少每年询问老年患者是否曾感到脚步不稳或是否跌倒过。考虑药物是否可能导致脚步不稳或跌倒的感觉。苯二氮䓬类药物和选择性5-羟色胺再摄取抑制剂等药物,尤其是同时服用时,与跌倒和髋部骨折的风险相关。查看患者的治疗方案,看是否有不再需要的药物。精神药物通常应逐渐减量,以便将不良反应降至最低。让一系列医疗专业人员参与识别和管理跌倒风险。帮助患者保持身体活跃、独立并保持社交联系

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ed1/6594851/91471e8e81a8/austprescr-42-93-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ed1/6594851/91471e8e81a8/austprescr-42-93-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ed1/6594851/91471e8e81a8/austprescr-42-93-f1.jpg

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Risk of Hip Fracture in Older People Using Selective Serotonin Reuptake Inhibitors and Other Psychoactive Medicines Concurrently: A Matched Case-Control Study in Australia.老年人同时使用选择性5-羟色胺再摄取抑制剂和其他精神活性药物时髋部骨折的风险:澳大利亚一项匹配病例对照研究
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