Department of Physiotherapy, OsloMet - Oslo Metropolitan University, PO Box 4, St. Olavs Plass, 0130, Oslo, Norway.
Faculty of Management, University of British Columbia Okanagan, Kelowna, Canada.
Qual Life Res. 2019 Dec;28(12):3187-3195. doi: 10.1007/s11136-019-02258-x. Epub 2019 Jul 30.
Health-related quality of life (HRQOL) is an important outcome in economic evaluations of health care interventions for older adults. The aim of this study was to compare two commonly used preference-based utility measures, SF-6D and EQ-5D, to provide knowledge on their applicability when evaluating falls prevention interventions in primary health care.
The study is a secondary analysis of longitudinal data from a randomised controlled trial, which included 155 older home care recipients participating in a falls prevention intervention in Norway. HRQOL was measured by SF-6D and EQ-5D. Physical function was measured by Berg Balance Scale, 4-m walk test, 30-s sit-to-stand and Falls Efficacy Scale International. Assessments were performed at baseline, 3 months and 6 months. The agreement between SF-6D and EQ-5D was examined using Bland-Altman plots and Spearman correlations. Elasticities from regression analysis were employed to compare the instruments' responsiveness.
SF-6D and EQ-5D were strongly correlated (0.71), but there were differences in the instruments' agreement and domains of HRQOL covered. Participants with a higher mean HRQOL and/or better physical function scored generally higher on EQ-5D. Participants with a lower mean HRQOL and/or poorer physical function achieved a relatively higher score on SF-6D. EQ-5D was more responsive to changes in physical function compared to SF-6D.
SF-6D and EQ-5D have both similarities and differences regarding sensitivity, domains covered and responsiveness to changes when evaluating a falls prevention intervention. Selecting the appropriate instrument depends on the characteristics of the participants and the intervention being evaluated.
健康相关生活质量（HRQOL）是评估老年人医疗保健干预措施的经济评价中的一个重要结果。本研究旨在比较两种常用的偏好基础效用测量方法，即 SF-6D 和 EQ-5D，以了解它们在评估初级保健中的跌倒预防干预措施时的适用性。
该研究是一项随机对照试验的纵向数据二次分析，该试验纳入了挪威 155 名接受跌倒预防干预的老年家庭护理接受者。HRQOL 通过 SF-6D 和 EQ-5D 进行测量。身体功能通过 Berg 平衡量表、4 米步行测试、30 秒坐站和跌倒效能量表国际版进行测量。评估在基线、3 个月和 6 个月进行。使用 Bland-Altman 图和 Spearman 相关系数检查 SF-6D 和 EQ-5D 之间的一致性。使用回归分析的弹性来比较两种工具的反应能力。
SF-6D 和 EQ-5D 具有很强的相关性（0.71），但在工具的一致性和涵盖的 HRQOL 领域存在差异。具有较高平均 HRQOL 和/或更好身体功能的参与者通常在 EQ-5D 上获得更高的分数。具有较低平均 HRQOL 和/或较差身体功能的参与者在 SF-6D 上获得相对较高的分数。与 SF-6D 相比，EQ-5D 对身体功能的变化更敏感。
SF-6D 和 EQ-5D 在敏感性、涵盖的领域和对变化的反应能力方面既有相似之处，也有差异，在评估跌倒预防干预时选择合适的工具取决于参与者的特征和正在评估的干预措施。
