Oltra-Cucarella Javier, Sánchez-SanSegundo Miriam, Rubio-Aparicio María, Arango-Lasprilla Juan Carlos, Ferrer-Cascales Rosario
University of Alicante, Alicante, Spain.
BioCruces Bizkaia Health Research Institute, Cruces University Hospital Barakaldo, Bizkaia, Spain. 48903.
Assessment. 2021 Apr;28(3):955-963. doi: 10.1177/1073191119864646. Epub 2019 Jul 31.
Obtaining one or more low scores, or scores indicative of impairment, is common in neuropsychological batteries that include several measures even among cognitively normal individuals. However, the expected number of low scores in batteries with differing number of tests is unknown. Using 10 neuropsychological measures from the National Alzheimer's Coordinating Center database, 1,023 permutations were calculated from a sample of 5,046 cognitively normal individuals. The number of low scores (i.e., score ≤-1.5) varied for the same number of measures and among different number of measures and did not increase linearly as the number of measures increased. According to the number of low scores shown by fewer than 10% of the sample, cognitive impairment should be suspected for 1 or more, 2 or more, and 3 or more in batteries with up to 2 measures, 3 to 9 measures, and 10 measures, respectively. These results may increase the identification of mild cognitive impairment.
在包含多项测试的神经心理成套测验中，即便在认知正常的个体中，获得一个或多个低分或表明存在损伤的分数也很常见。然而，不同测试数量的成套测验中预期的低分数量尚不清楚。利用来自国家阿尔茨海默病协调中心数据库的10项神经心理测试，从5046名认知正常的个体样本中计算出了1023种排列组合。对于相同数量的测试以及不同数量的测试，低分数量（即分数≤ -1.5）各不相同，且并未随着测试数量的增加而呈线性增加。根据样本中不到10%的个体所显示的低分数量，对于分别有至多2项测试、3至9项测试和10项测试的成套测验，若出现1个或更多、2个或更多以及3个或更多低分，则应怀疑存在认知损伤。这些结果可能会增加对轻度认知损伤的识别。
