Liu Zhaochuan, Xie Binyu, Li Yang, Ding Jingwen, Li Dongmei
Department of Ophthalmology, Beijing Tongren Hospital, Beijing Ophthalmology and Visual Science Key Lab, Capital Medical University, No.1 Dong Jiao Min Xiang Street, Dongcheng District, Beijing, 100730, China.
BMC Ophthalmol. 2019 Jul 31;19(1):165. doi: 10.1186/s12886-019-1170-6.
The present study sought to introduce clinical characteristics and stepwise surgical strategies of isolated complete cryptophthalmos, a rare, congenital ocular anomaly.
Retrospective, noncomparative, clinical study. Six patients with isolated complete cryptophthalmos were diagnosed at the Beijing Tongren Hospital between 2010 to 2018. The presentation age of patients ranged from 1 month to 68 years. This study includes two males and four females, and involvement was noted to be bilateral in two cases and unilateral in four cases. According to orbital CT scan and ocular CDI results, two patients were combined with ocular cyst. Reconstruction surgeries were performed in three patients, involving the eyeball enucleation, creation of fornix, eyelid reconstruction with skin flaps/amniotic membrane, and implantation of prosthesis. Besides, implantation of hydroxyapatite was performed in one pediatric patient to promote orbit development. Good outcomes in terms of cosmetic satisfaction were achieved in all patients during follow-up.
Surgical intervention could only improve the cosmetic appearance in isolated complete cryptophthalmos. The surgical strategies may be planned to use three-stage approaches described in this study. Meanwhile, orbital development must be taken into consideration in pediatric cases.
本研究旨在介绍孤立性完全性隐眼畸形这一罕见的先天性眼部异常的临床特征及分步手术策略。
回顾性、非对照临床研究。2010年至2018年期间，北京同仁医院诊断出6例孤立性完全性隐眼畸形患者。患者的就诊年龄从1个月至68岁不等。本研究包括2名男性和4名女性，其中2例为双眼受累，4例为单眼受累。根据眼眶CT扫描和眼部CDI结果，2例患者合并眼囊肿。3例患者接受了重建手术，包括眼球摘除、穹窿形成、皮瓣/羊膜眼睑重建及假体植入。此外，1例儿科患者植入了羟基磷灰石以促进眼眶发育。随访期间所有患者在美容满意度方面均取得了良好效果。
手术干预仅能改善孤立性完全性隐眼畸形的外观。手术策略可按本研究中所述的三阶段方法进行规划。同时，儿科病例中必须考虑眼眶发育情况。
