胆管内乳头状肿瘤切除术的临床病理研究

Clinicopathological Study of Resections of Intraductal Papillary Neoplasm of the Bile Duct.

作者信息

Sato Toshihiro, Hisaka Toru, Sakai Hisamune, Ishikawa Hiroto, Kawahara Ryuichi, Goto Yuichi, Nomura Yoriko, Yasunaga Masafumi, Fujita Fumihiko, Tanigawa Masahiko, Naito Yoshiki, Akiba Jun, Yano Hirohisa, Tanaka Hiroyuki, Akagi Yoshito, Okuda Koji

机构信息

Department of Surgery, Faculty of Medicine, Kurume University, Kurume, Japan.

Department of Surgery, Faculty of Medicine, Kurume University, Kurume, Japan

出版信息

Anticancer Res. 2019 Aug;39(8):4569-4573. doi: 10.21873/anticanres.13635.

DOI:10.21873/anticanres.13635

PMID:31366561

Abstract

BACKGROUND/AIM: The aim of this study was to examine the clinicopathological features of intraductal papillary neoplasm of the bile duct (IPNB) and investigate their relationships with intraductal papillary mucinous neoplasm (IPMN).

PATIENTS AND METHODS

Our study included 104 patients who underwent resection of tumors that showed papillary growth within the bile duct and pancreas.

RESULTS

Comparisons were performed based on subtypes and histological grades. The presence of various histological grades was confirmed in both the IPNB group and the IPMN group, and statistical significance was found in the between-group comparisons of subtypes and histological grades. It was shown that while all patients who underwent IPNB resection did not match the classifications proposed by Nakanuma et al., they did reflect classification characteristics.

CONCLUSION

IPNB and IPMN have common clinical histological features. Common features between IPNB subtype classifications were also identified, which may provide novel diagnostics.

摘要

背景/目的：本研究旨在探讨胆管内乳头状肿瘤（IPNB）的临床病理特征，并研究其与导管内乳头状黏液性肿瘤（IPMN）的关系。