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How a revolutionary technique got people with spinal-cord injuries back on their feet.

作者信息

Willyard Cassandra

出版信息

Nature. 2019 Aug;572(7767):20-25. doi: 10.1038/d41586-019-02306-z.

DOI:10.1038/d41586-019-02306-z
PMID:31367032
Abstract
摘要

相似文献

1
How a revolutionary technique got people with spinal-cord injuries back on their feet.一项革命性技术如何让脊髓损伤患者重新站起来。
Nature. 2019 Aug;572(7767):20-25. doi: 10.1038/d41586-019-02306-z.
2
Sequelae and rehabilitation of spinal cord injuries.脊髓损伤的后遗症与康复
Curr Opin Neurol Neurosurg. 1991 Oct;4(5):714-9.
3
Intraspinal microstimulation generates functional movements after spinal-cord injury.脊髓内微刺激在脊髓损伤后可产生功能性运动。
IEEE Trans Neural Syst Rehabil Eng. 2004 Dec;12(4):430-40. doi: 10.1109/TNSRE.2004.837754.
4
Alternative, complementary, energy-based medicine for spinal cord injury.用于脊髓损伤的替代、补充、基于能量的医学。
Acta Neurochir Suppl. 2005;93:155-8. doi: 10.1007/3-211-27577-0_27.
5
Effects of quadriceps and anterior tibial muscles electrical stimulation on the feet and ankles of patients with spinal cord injuries.股四头肌和胫骨前肌电刺激对脊髓损伤患者足部和踝关节的影响。
Spinal Cord. 2010 Dec;48(12):881-5. doi: 10.1038/sc.2010.50. Epub 2010 May 18.
6
Spinal cord injury rehabilitation.脊髓损伤康复
Phys Med Rehabil Clin N Am. 2014 Aug;25(3):xiii-xiv. doi: 10.1016/j.pmr.2014.07.001.
7
ABC of spinal cord injury. Later management and complications--II.脊髓损伤基础。后期管理与并发症——II
Br Med J (Clin Res Ed). 1986 Mar 15;292(6522):743-5. doi: 10.1136/bmj.292.6522.743.
8
[Electric stimulation of the spinal cord].[脊髓的电刺激]
Zh Vopr Neirokhir Im N N Burdenko. 1977 Sep-Oct(5):7-13.
9
Bladder and urethral sphincter responses evoked by microstimulation of S2 sacral spinal cord in spinal cord intact and chronic spinal cord injured cats.脊髓完整和慢性脊髓损伤猫中，微刺激骶2脊髓所诱发的膀胱和尿道括约肌反应。
Exp Neurol. 2004 Nov;190(1):171-83. doi: 10.1016/j.expneurol.2004.07.001.
10
Spinal cord injury rehabilitation.脊髓损伤康复
Phys Med Rehabil Clin N Am. 2014 Aug;25(3):xv-xvi. doi: 10.1016/j.pmr.2014.06.001.

引用本文的文献

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Recent progress and challenges in the treatment of spinal cord injury.脊髓损伤治疗的最新进展和挑战。
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Transcutaneous spinal cord stimulation combined with locomotor training to improve walking ability in people with chronic spinal cord injury: study protocol for an international multi-centred double-blinded randomised sham-controlled trial (eWALK).经皮脊髓电刺激联合运动训练改善慢性脊髓损伤患者步行能力的国际多中心、双盲、随机对照试验研究方案（eWALK）。
Spinal Cord. 2022 Jun;60(6):491-497. doi: 10.1038/s41393-021-00734-1. Epub 2022 Jan 11.
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1
Epidural Spinal Cord Stimulation Facilitates Immediate Restoration of Dormant Motor and Autonomic Supraspinal Pathways after Chronic Neurologically Complete Spinal Cord Injury.硬膜外脊髓电刺激促进慢性完全性脊髓损伤后休眠的运动和自主神经上位通路的即刻恢复。
J Neurotrauma. 2019 Aug 1;36(15):2325-2336. doi: 10.1089/neu.2018.6006. Epub 2019 Mar 6.
2
Targeted neurotechnology restores walking in humans with spinal cord injury.靶向神经技术恢复脊髓损伤患者的行走能力。
Nature. 2018 Nov;563(7729):65-71. doi: 10.1038/s41586-018-0649-2. Epub 2018 Oct 31.
3
Neuromodulation of lumbosacral spinal networks enables independent stepping after complete paraplegia.
The barriers and facilitators of radical innovation implementation in secondary healthcare: a systematic review.
二级医疗机构中激进创新实施的障碍和促进因素：系统评价。
J Health Organ Manag. 2021 Dec 16;ahead-of-print(ahead-of-print):289-312. doi: 10.1108/JHOM-12-2020-0493.
4
Effects of Noninvasive Low-Intensity Focus Ultrasound Neuromodulation on Spinal Cord Neurocircuits In Vivo.非侵入性低强度聚焦超声神经调节对体内脊髓神经回路的影响。
Evid Based Complement Alternat Med. 2021 Nov 27;2021:8534466. doi: 10.1155/2021/8534466. eCollection 2021.
5
Restoring Sensorimotor Function Through Neuromodulation After Spinal Cord Injury: Progress and Remaining Challenges.脊髓损伤后通过神经调节恢复感觉运动功能：进展与尚存挑战
Front Neurosci. 2021 Oct 14;15:749465. doi: 10.3389/fnins.2021.749465. eCollection 2021.
6
Complications of epidural spinal stimulation: lessons from the past and alternatives for the future.硬膜外脊髓刺激的并发症：过去的教训和未来的替代方案。
Spinal Cord. 2020 Oct;58(10):1049-1059. doi: 10.1038/s41393-020-0505-8. Epub 2020 Jun 23.
7
Ultrasound-driven piezoelectric current activates spinal cord neurocircuits and restores locomotion in rats with spinal cord injury.超声驱动的压电电流激活脊髓神经回路并恢复脊髓损伤大鼠的运动能力。
Bioelectron Med. 2020 Jun 1;6:13. doi: 10.1186/s42234-020-00048-2. eCollection 2020.
腰骶脊柱网络的神经调节使得完全截瘫后能够独立行走。
Nat Med. 2018 Nov;24(11):1677-1682. doi: 10.1038/s41591-018-0175-7. Epub 2018 Sep 24.
4
Recovery of Over-Ground Walking after Chronic Motor Complete Spinal Cord Injury.慢性完全性脊髓损伤后地上行走功能的恢复。
N Engl J Med. 2018 Sep 27;379(13):1244-1250. doi: 10.1056/NEJMoa1803588. Epub 2018 Sep 24.
5
Epidural Spinal Cord Stimulation Training and Sustained Recovery of Cardiovascular Function in Individuals With Chronic Cervical Spinal Cord Injury.硬膜外脊髓刺激训练与慢性颈脊髓损伤个体心血管功能的持续恢复。
JAMA Neurol. 2018 Dec 1;75(12):1569-1571. doi: 10.1001/jamaneurol.2018.2617.
6
Altering spinal cord excitability enables voluntary movements after chronic complete paralysis in humans.改变脊髓兴奋性可使人在慢性完全瘫痪后进行自主运动。
Brain. 2014 May;137(Pt 5):1394-409. doi: 10.1093/brain/awu038. Epub 2014 Apr 8.
7
Effect of epidural stimulation of the lumbosacral spinal cord on voluntary movement, standing, and assisted stepping after motor complete paraplegia: a case study.腰背部脊髓硬膜外刺激对运动完全性截瘫后自主运动、站立和辅助行走的影响：病例研究。
Lancet. 2011 Jun 4;377(9781):1938-47. doi: 10.1016/S0140-6736(11)60547-3. Epub 2011 May 19.
8
Spinal cord stimulation facilitates functional walking in a chronic, incomplete spinal cord injured.脊髓刺激有助于慢性不完全性脊髓损伤患者的功能性行走。
Spinal Cord. 2002 Feb;40(2):65-8. doi: 10.1038/sj.sc.3101263.
9
Evidence for a spinal central pattern generator in humans.人类脊髓中枢模式发生器的证据。
Ann N Y Acad Sci. 1998 Nov 16;860:360-76. doi: 10.1111/j.1749-6632.1998.tb09062.x.
10
Enhancement of voluntary motor function following spinal cord stimulation--case study.脊髓刺激后自主运动功能增强——病例研究
Appl Neurophysiol. 1986;49(6):307-14. doi: 10.1159/000100160.