Cezar T C, Schweppe K W, Pletzer K R, Becker S, Krentel H, Torres-De La Roche L A, De Wilde R L
Gynecology Consultant. Scientific Researcher at the University Hospital for Gynecology, Pius Hospital, University Medicine Oldenburg, Carl von Ossietzky University, Oldenburg, Germany. Email:
Professor of the Clinic of Gynecology and Obstetrics at Ammerland - Klinik Westerstede, Westerstede, Germany,
Facts Views Vis Obgyn. 2018 Dec;10(4):181-190.
Endometriosis represents nowadays a real burden for the patients as well as for the physicians, as it requires surgical and/or medical treatment, often long - termed and repeated. Moreover, the high costs necessary to diagnose and treat endometriosis represent a real economic burden, being comparable to other chronic diseases like diabetes or rheumatoid arthritis. Therefore, the physicians dealing with this disease should take into account not only the efficacy of the treatment, but also the economic aspects and patients compliance. The present paper analyses the efficiency of progestins (lynestrenol and medrogestone) in endometriosis as a cost - effective, but forgotten medical therapy of the disease. Our study underlines the good tolerability of progestins, as they have limited side effects, the compliance of patients being high. They are also low-cost medications, which could represent an effective alternative method in the endometriosis treatment, especially in less - developed countries that cannot afford the higher therapeutic costs.
如今，子宫内膜异位症对患者和医生来说都是一项实实在在的负担，因为它需要手术和/或药物治疗，而且往往疗程长且需反复治疗。此外，诊断和治疗子宫内膜异位症所需的高昂费用构成了一项实实在在的经济负担，堪比糖尿病或类风湿性关节炎等其他慢性疾病。因此，治疗这种疾病的医生不仅应考虑治疗效果，还应考虑经济因素和患者的依从性。本文分析了炔诺酮和甲地孕酮等孕激素在子宫内膜异位症治疗中的有效性，它们是一种具有成本效益但被忽视的该疾病药物疗法。我们的研究强调了孕激素的良好耐受性，因为它们副作用有限，患者的依从性较高。它们也是低成本药物，在子宫内膜异位症治疗中可能是一种有效的替代方法，尤其是在负担不起更高治疗费用的欠发达国家。
