Dodinot B, Marçon F, Mouna B, Ribeiro-Lages F, Godenir J P, Pernot C
Clinique des maladies cardiovasculaires, CHU de Nancy-Brabois, Vandoeuvre-lès-Nancy.
Arch Mal Coeur Vaiss. 1988 May;81(5):673-83.
Between July, 1967 and December, 1987, 71 children and adolescents (43 boys, 28 girls) aged from 9 days to 20 years (mean 7.8 years) underwent pacemaker implantation. In 91 p. 100 of the cases this treatment was performed for complete atrioventricular block (CAVB). Surgical CAVB was the reason for 59 p. 100 of implantations (correction of tetralogy of Fallot and, more recently, of complex cardiopathies), the second main reason (16.9 p. 100) being nonsurgical CAVB associated with heart disease; the children in this group were young (mean age 4.2 years), and the prognosis mainly depended on the heart disease. Isolated congenital CAVB accounted for only 8.5 p. 100 of pacemaker implantations; these were older children (mean age 13.7 years), and the decision to implant was often difficult to reach in the absence of major functional disorders; following implantation, it was frequently found that isolated congenital CAVBs regarded as being well tolerated in fact were unrecognized handicaps. Acquired CAVB (7 p. 100) mostly consisted of Kearns' syndrome (4/5 cases). In addition, 3 children with sinus node disease and 1 with Romano-Ward syndrome benefited from cardiac pacing. Seven children died; death was in no case due to pacing but to the heart disease associated with CAVB. Endocardial pacing (68.2 p. 100 of primary implantations during the last decade) was preferred to epicardial pacing. Since 1985 we have been using exclusively screwed endocardial monopolar electrodes. The pacemakers were usually of the single-chamber ventricular type (85.9 p. 100 of primary implantations), but since 1987 dual-chamber pacemakers have been increasingly preferred for children with permanent CAVB or for replacement of pacemaker cases. Single-chamber noncompetitive ("demand") pacemakers were implanted in only 2 children: one pacemaker was connected to a ventricular electrode (atrial paralysis), the other to an atrial electrode. Whatever the type of electrode used, the pacemakers were implanted in the abdominal region in very young infants and in the pectoral region in children older than 3 or 4 years. Breakage of the wire was the main complication. Rises in threshold are the major drawback of epicardial pacing, as they require reoperation when the energy delivered cannot be effectively programmed. Endocardial pacing, preferably with a dual-chamber instrument, seems to be the best method, being the least aggressive, with minimal complications in short and very long term; it is justified as first-line treatment of permanent or predominant CAVB.(ABSTRACT TRUNCATED AT 400 WORDS)
1967年7月至1987年12月期间,71名年龄从9天至20岁(平均7.8岁)的儿童和青少年(43名男孩,28名女孩)接受了起搏器植入手术。在91%的病例中,进行这种治疗是为了治疗完全性房室传导阻滞(CAVB)。外科手术导致的CAVB是59%植入手术的原因(法洛四联症矫正术,以及最近的复杂心脏病矫正术),第二个主要原因(16.9%)是非外科手术导致的与心脏病相关的CAVB;该组儿童年龄较小(平均年龄4.2岁),预后主要取决于心脏病。孤立性先天性CAVB仅占起搏器植入手术的8.5%;这些是年龄较大的儿童(平均年龄13.7岁),在没有严重功能障碍的情况下,往往难以决定是否植入;植入后,经常发现被认为耐受性良好的孤立性先天性CAVB实际上是未被认识到的障碍。获得性CAVB(7%)大多由卡恩斯综合征(4/5例)组成。此外,3名患有窦房结疾病的儿童和1名患有 Romano-Ward综合征的儿童受益于心脏起搏。7名儿童死亡;死亡无一例是由于起搏,而是由于与CAVB相关的心脏病。心内膜起搏(过去十年中初次植入的68.2%)比心外膜起搏更受青睐。自1985年以来,我们一直只使用旋入式心内膜单极电极。起搏器通常为单腔心室型(初次植入的85.9%),但自1987年以来,双腔起搏器越来越多地被用于患有永久性CAVB的儿童或用于更换起搏器病例。仅2名儿童植入了单腔非竞争性(“按需”)起搏器:一个起搏器连接到心室电极(心房麻痹),另一个连接到心房电极。无论使用何种类型的电极,起搏器在非常小的婴儿中植入腹部区域,在3或4岁以上的儿童中植入胸部区域。导线断裂是主要并发症。阈值升高是心外膜起搏的主要缺点,因为当所输送的能量无法有效程控时,需要再次手术。心内膜起搏,最好使用双腔仪器,似乎是最好的方法,它侵袭性最小,短期和长期并发症最少;它被证明是永久性或主要CAVB的一线治疗方法。(摘要截选至40