Yamamoto M, Kondo H
Department of Anatomy, Kanazawa University School of Medicine, Japan.
Arch Histol Cytol. 1988 May;51(2):169-74. doi: 10.1679/aohc.51.169.
A dense plexus of CGRP-immunoreactive nerve fibers was found subjacent to and within the epithelium of the excretory ducts of the parotid, submandibular and sublingual glands in the rat, in close proximity to the opening into the oral cavity. The immunoreactive nerve fibers disappeared after a neonatal administration of capsaicin. In immuno-electron microscopy, the immunoreactive nerve fibers were characterized by abundant small clear vesicles mixed with some large granular vesicles, but not by any particular abundance of small mitochondria. Intraepithelial immunoreactive fibers were directly apposed to adjacent epithelial cells without any membrane specializations. They did not exceed the subapical junctional complex of the epithelial cells.
在大鼠腮腺、下颌下腺和舌下腺排泄管上皮下方及上皮内，发现了一个密集的降钙素基因相关肽（CGRP）免疫反应性神经纤维丛，紧邻通向口腔的开口处。新生期给予辣椒素后，免疫反应性神经纤维消失。在免疫电子显微镜下，免疫反应性神经纤维的特征是有大量小清亮囊泡与一些大颗粒囊泡混合，但小线粒体并无特别丰富。上皮内免疫反应性纤维直接与相邻上皮细胞贴附，无任何膜特化结构。它们未超过上皮细胞的顶端下连接复合体。
