Suppr超能文献

微血管减压术治疗面肌痉挛患者社交恐惧症和健康相关生活质量的长期影响:一项 3 年前瞻性研究。

The long-term effects of microvascular decompression on social phobia and health-related quality of life in patients with hemifacial spasm: a 3-year prospective study.

机构信息

Department of Neurosurgery, Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, Republic of Korea.

Department of Neurosurgery, Brain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.

出版信息

Acta Neurochir (Wien). 2019 Oct;161(10):2035-2042. doi: 10.1007/s00701-019-04023-y. Epub 2019 Jul 31.

Abstract

BACKGROUND

Although not a life-threatening condition, hemifacial spasm (HFS) frequently leads to social phobia because it causes significant facial disfigurement and consequently reduces health-related quality of life (HRQoL). The purpose of the current study was to examine the long-term effects of MVD on psychological aspects and HRQoL in HFS patients with social anxiety over a 36-month follow-up.

METHODS

Thirty patients with HFS who underwent MVD from January 2015 to May 2015 were included in this prospective study. Clinical data, including standardized measures of general anxiety and depression (Hospital Anxiety Depression Scale (HADS)), social anxiety (Liebowitz Social Anxiety Scale (LSAS)), and the severity of HFS, were collected postoperatively, and 6 months and 36 months after MVD. Likewise, data on HRQoL were collected at baseline, and 6 months and 36 months after MVD using the Korean version of the Short Form 36 (SF-36).

RESULTS

Twenty-two patients who completed the 36-month follow-up were classified into social phobia group and non-social phobia group based on the LSAS total scores of 60. Repeated measures analysis of variance demonstrated significant differences between the two groups over time for the total LSAS score (p < 0.001), anxiety subscale score of the HADS (p = 0.002), and the Mental Component Summary (MCS) (p = 0.046) of the SF-36. A comparison of these two groups in terms of differences observed in their scales at 6 months after MVD has shown that the improvements of the social phobia group in HADS anxiety subscale (p = 0.010), LSAS total score (p = 0.008), and MCS (p = 0.040) were significantly more improved than the those of non-social phobia group. And at 36 months after surgery, the improvement of the scales mentioned above was maintained, and additionally Vitality (p = 0.040) and Mental Health (p = 0.040) dimensions showed a statistically significant improvement.

CONCLUSIONS

The improvements previously observed in psychological aspects and HRQoL over a short-term follow-up after MVD in HFS patients with social phobia were maintained for at least 36 months after MVD.

摘要

背景

尽管面肌痉挛(hemifacial spasm,HFS)不是危及生命的疾病,但由于其导致明显的面部畸形,从而降低了健康相关生活质量(health-related quality of life,HRQoL),因此常导致社交恐惧症。本研究的目的是在 36 个月的随访中,评估微血管减压术(microvascular decompression,MVD)对面肌痉挛患者社交焦虑的心理方面和 HRQoL 的长期影响。

方法

本前瞻性研究纳入了 2015 年 1 月至 2015 年 5 月期间接受 MVD 的 30 例 HFS 患者。术后、MVD 后 6 个月和 36 个月采集临床数据,包括一般焦虑和抑郁的标准化量表(医院焦虑抑郁量表(Hospital Anxiety Depression Scale,HADS))、社交焦虑(Liebowitz 社交焦虑量表(Liebowitz Social Anxiety Scale,LSAS))和 HFS 严重程度。同样,使用韩国版简明健康调查问卷(Short Form 36,SF-36)在 MVD 前、MVD 后 6 个月和 36 个月收集 HRQoL 数据。

结果

根据 LSAS 总分 60 将 22 例完成 36 个月随访的患者分为社交恐惧症组和非社交恐惧症组。重复测量方差分析显示,两组之间的 LSAS 总分(p < 0.001)、HADS 焦虑分量表评分(p = 0.002)和 SF-36 的精神健康分量表评分(p = 0.046)随时间变化有显著差异。比较 MVD 后 6 个月两组间量表差异,发现社交恐惧症组 HADS 焦虑分量表(p = 0.010)、LSAS 总分(p = 0.008)和 MCS(p = 0.040)的改善明显优于非社交恐惧症组。术后 36 个月,上述量表的改善得以维持,同时活力(p = 0.040)和心理健康(p = 0.040)维度也有统计学意义上的改善。

结论

HFS 合并社交恐惧症患者 MVD 后短期随访时观察到的心理和 HRQoL 改善至少在 MVD 后 36 个月内得以维持。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验