Department of Computer Science, Vrije Universiteit, 1081 HV Amsterdam, The Netherlands.
Bioinformatics. 2019 Dec 15;35(24):5315-5317. doi: 10.1093/bioinformatics/btz572.
PRALINE 2 is a toolkit for custom multiple sequence alignment workflows. It can be used to incorporate sequence annotations, such as secondary structure or (DNA) motifs, into the alignment scoring, as well as to customize many other aspects of a progressive multiple alignment workflow.
PRALINE 2 is implemented in Python and available as open source software on GitHub: https://github.com/ibivu/PRALINE/.
PRALINE 2 是一个用于定制多序列比对工作流程的工具包。它可以用于将序列注释（如二级结构或（DNA）基序）纳入比对评分中，并定制渐进多序列比对工作流程的许多其他方面。
PRALINE 2 是用 Python 编写的，作为开源软件在 GitHub 上可用：https://github.com/ibivu/PRALINE/。
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