Natsume Kayoko, Shiiya Norihiko, Tsuchida Takashi, Nagakura Yuka
First Department of Surgery, Hamamatsu University School of Medicine, Shizuoka, Japan.
Interact Cardiovasc Thorac Surg. 2019 Dec 1;29(6):983-985. doi: 10.1093/icvts/ivz192.
Although aortic sarcomas are extremely rare, they may arise in association with a Dacron graft. Here, we report a case of an intimal sarcoma in an ascending aortic Dacron graft implanted 17 years earlier. The patient presented with multiple cerebral infarctions; clinically, a thrombus was found to cause the embolic stroke. He successfully underwent re-replacement of the ascending aorta. Although the initial postoperative histopathological diagnosis was a thrombus, he died of multiple metastases of the malignant tumour after 5 months of the surgery. A histopathological re-evaluation of the explant using immunohistochemistry revealed that the mass was an intimal sarcoma.
尽管主动脉肉瘤极为罕见，但它们可能与涤纶人工血管相关联而出现。在此，我们报告一例发生于17年前植入的升主动脉涤纶人工血管的内膜肉瘤病例。患者出现多发性脑梗死；临床上，发现血栓导致了栓塞性中风。他成功接受了升主动脉再次置换术。尽管术后最初的组织病理学诊断为血栓，但术后5个月他死于恶性肿瘤的多处转移。使用免疫组织化学对外植体进行组织病理学重新评估显示，该肿物为内膜肉瘤。
