Sakla Rahul, Singh Ajeet, Kaushik Rahul, Kumar Pawan, Jose D Amilan
Department of Chemistry , NIT-Kurukshetra , Kurukshetra - 136119 , Haryana , India.
Department of Chemistry, Prof. Rajendra Singh (Raju Bhaiya) Institute of Physical Sciences for Study and Research , V. B. S. Purrrvanchal University Jaunpur , U.P. , India.
Inorg Chem. 2019 Aug 19;58(16):10761-10768. doi: 10.1021/acs.inorgchem.9b00984. Epub 2019 Aug 1.
A new CO-releasing terpyridine based manganese(I) tricarbonyl complex, [MnBr(CO)(terpy-CHOH)] () functioning via light has been reported. For the first time, we have demonstrated the allosteric regulation concept to control the CO-releasing properties of a CO-releasing molecule (CORM). Fluoride ion is reported to function as an allosteric activator to control the rate of CO release in the CORM. Complex represents an interesting new class of CO-releasing system that releases CO upon irradiation with blue light (410 nm) over a period of 40 min with the half-time of 9.8 min. Fluoride ion selectively binds to the phenol moiety of the complex through hydrogen bonding and deprotonates to phenolate with a color change. Interestingly in the presence of fluoride ion, the rate of CO release is fast with the half-time of less than a minute. The rate of CO release is allosterically regulated by fluoride anion and can be monitored through a color change, fluorescence, and absorption based spectral changes along with IR studies and myoglobin assay.
据报道，一种新型的基于联吡啶的一氧化碳释放锰（I）三羰基配合物[MnBr(CO)(terpy-CHOH)]（）可通过光发挥作用。我们首次证明了变构调节概念可用于控制一氧化碳释放分子（CORM）的一氧化碳释放特性。据报道，氟离子作为变构激活剂可控制CORM中一氧化碳的释放速率。配合物代表了一类有趣的新型一氧化碳释放系统，该系统在蓝光（410 nm）照射下40分钟内释放一氧化碳，半衰期为9.8分钟。氟离子通过氢键选择性地与配合物的酚部分结合，并去质子化为酚盐，伴随颜色变化。有趣的是，在氟离子存在下，一氧化碳释放速率很快，半衰期不到一分钟。一氧化碳的释放速率受氟阴离子变构调节，可通过颜色变化、荧光、基于吸收的光谱变化以及红外研究和肌红蛋白测定进行监测。
