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The Effects of Iloprost on Oxygenation During One-Lung Ventilation for Lung Surgery: A Randomized Controlled Trial.伊洛前列素对肺手术单肺通气期间氧合的影响：一项随机对照试验。
J Clin Med. 2019 Jul 5;8(7):982. doi: 10.3390/jcm8070982.
2
Hypoxia During One-Lung Ventilation-A Review and Update.单肺通气期间的低氧血症——综述与更新
J Cardiothorac Vasc Anesth. 2018 Oct;32(5):2330-2338. doi: 10.1053/j.jvca.2017.12.026. Epub 2017 Dec 19.
3
Hypoxic pulmonary vasoconstriction: physiology and anesthetic implications.低氧性肺血管收缩：生理学与麻醉学意义。
Anesthesiology. 2015 Apr;122(4):932-46. doi: 10.1097/ALN.0000000000000569.
4
Iloprost improves gas exchange in patients with pulmonary hypertension and ARDS.伊洛前列素可改善肺动脉高压合并 ARDS 患者的气体交换。
Chest. 2013 Jul;144(1):55-62. doi: 10.1378/chest.12-2296.
5
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Anesthesiology. 2009 Jun;110(6):1402-11. doi: 10.1097/ALN.0b013e31819fb15d.
6
Effects of propofol vs sevoflurane on arterial oxygenation during one-lung ventilation.丙泊酚与七氟醚对单肺通气期间动脉氧合的影响。
Br J Anaesth. 2007 Apr;98(4):539-44. doi: 10.1093/bja/aem039. Epub 2007 Mar 8.
7
Double lumen tube location predicts tube malposition and hypoxaemia during one lung ventilation.双腔管位置可预测单肺通气期间的导管位置异常和低氧血症。
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8
Inhaled nitric oxide administration during one-lung ventilation in patients undergoing thoracic surgery.胸外科手术患者单肺通气期间吸入一氧化氮治疗。
J Cardiothorac Vasc Anesth. 2001 Apr;15(2):218-23. doi: 10.1053/jcan.2001.21972.
9
Oxygenation during one-lung ventilation: the effects of inhaled nitric oxide and increasing levels of inspired fraction of oxygen.单肺通气期间的氧合：吸入一氧化氮和增加吸入氧分数水平的影响。
Anesth Analg. 2001 Apr;92(4):842-7. doi: 10.1097/00000539-200104000-00009.
10
Inhaled prostacyclin (PGI2) versus inhaled nitric oxide in adult respiratory distress syndrome.吸入性前列环素（PGI2）与吸入性一氧化氮治疗成人呼吸窘迫综合征的比较
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一种用于单肺通气期间低氧血症的简单有效药物治疗方法。

A Simple Effective Pharmacological Treatment of Hypoxemia During One-Lung Ventilation.

作者信息

Chiumello Davide, Coppola Silvia, Ferrari Erica

机构信息

Department of Anesthesia and Intensive Care, ASST Santi Paolo e Carlo, San Paolo University Hospital, 20142 Milan, Italy.

Department of Health Sciences, University of Milan, 20142 Milan, Italy.

出版信息

J Clin Med. 2019 Jul 31;8(8):1139. doi: 10.3390/jcm8081139.

DOI:10.3390/jcm8081139
PMID:31370195
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6722534/
Abstract

Hypoxemia during one-lung ventilation is a challenge in the clinical practice. Moving from the results of the study conducted by Choi et al., we discuss the possibility to modulate hypoxemia by administering iloprost via inhalation, in the light of the physiological mechanisms.

摘要

单肺通气期间的低氧血症是临床实践中的一项挑战。根据Choi等人开展的研究结果，我们结合生理机制探讨了通过吸入伊洛前列素调节低氧血症的可能性。