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药物诱导睡眠计算机断层扫描在阻塞性睡眠呼吸暂停低通气综合征诊断中的价值:一项初步研究。

The value of drug-induced sleep computed tomography in diagnosis of obstructive sleep apnea syndrome: a pilot study.

作者信息

Zhang Xiaoman, Lv Ning, Li Xin, Sun Shasha, Li Jianfeng, Yang Huiming, Yu Zhaoyan, Wang Haibo

机构信息

Shandong Provincial ENT Hospital, Shandong Provincial ENT Hospital Affiliated to Shandong University , Shandong , China.

The Affiliated Hospital of Inner Mongolia Medical University , Ulaanbaatar , Mongolia.

出版信息

Acta Otolaryngol. 2019 Oct;139(10):895-901. doi: 10.1080/00016489.2019.1632480. Epub 2019 Aug 2.

Abstract

Obstructive sleep apnea syndrome (OSAS) is a public health problem that affects a large amount of people. Surgery sometimes is considered a better treatment modality that does not require the use of a device such as CPAP. To explore the value of anesthetic-induced sleep computed tomography (DI-SCT) in the diagnosis of OSAS. A total of 124 patients with OSAS aged between 18 and 65 years old were enrolled in this study. The upper airway was scanned by computed tomography (CT) while they were wake and went sleep. Sleep was induced by dexmedetomidine under electrocardiograph and oxyhemoglobin saturation monitoring. Parameters relevant to OSAS were then collected and counted. CT scanning revealed that 119 occurred stenosis in oropharynx, in which 5 cases were accompanied with stenosis or occlusion at retroglossal area. About 38 (30.67%) cases existed deviation of nasal septum with retropalatal problems. About 61.33% of patients had multi-level obstructions and the most common obstructive site was oropharynx (90.67%). DI-SCT is a safe and non-invasive modality for diagnosing the obstructive sites in OSAS patients.

摘要

阻塞性睡眠呼吸暂停低通气综合征(OSAS)是一个影响大量人群的公共卫生问题。手术有时被认为是一种更好的治疗方式,不需要使用持续气道正压通气(CPAP)等设备。为探讨麻醉诱导睡眠计算机断层扫描(DI-SCT)在OSAS诊断中的价值。本研究共纳入124例年龄在18至65岁之间的OSAS患者。在患者清醒和睡眠状态下,通过计算机断层扫描(CT)对上气道进行扫描。在心电图和氧合血红蛋白饱和度监测下,用右美托咪定诱导睡眠。然后收集并计算与OSAS相关的参数。CT扫描显示,119例口咽出现狭窄,其中5例伴有舌后区域狭窄或闭塞。约38例(30.67%)存在鼻中隔偏曲伴腭后问题。约61.33%的患者存在多平面阻塞,最常见的阻塞部位是口咽(90.67%)。DI-SCT是诊断OSAS患者阻塞部位的一种安全、无创的方法。

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